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. 2005 Jul;12(7):833–836. doi: 10.1128/CDLI.12.7.833-836.2005

TABLE 1.

Amino acid sequences of the M subtypes and their frequencies of occurrence

Subtype No. of isolates recovereda M sequence corresponding to vaccine subunitb
11020304050
M1.0 586 NGDGNPREVIEDLAANNPAIQNIRLRHENKDLKARLENAMEVAGRDFKRA
M1.2 0 NNDGRSRDVTEEIAANNTTVQNIRLRNENKNLKAKNEDLKARLENAMNVA
M1.4 1 NENVGPRDVVKELVEKDPVLQNKRLRSENQKLKESLENARDVAGRDFKRA
M1.8 1 NGDGNPREVIEDLAANNPAIQNIRLRHHENKDLKARLENAMEVAGRDFKRA
M1.9 1 NGDGNPREVIEDLAANNPAIRNIRLRHENKDLKARLENAMEVAGRDFKRA
M1.10 1 NGDGNPREVIEDLAANNPVIQNIRLRHENKDLKARLENAMEVAGRDFKRA
M1.11 1 NGDGNPREVIEDLAANNPAIQNIRLRHENKVLKARLENAMEVAGRDFKRA
M1.13 1 NDDGNPREVIEDLAANNPAIQNIRLRHENKDLKARLENAMEVAGRDFKRA
213040506070
M3.1 196 NLLDQVTQLYTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.2 9 NLLDQVTQLYTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLDVKK
M3.4 51 NLLNQVTQLYTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.6 2 NLLNQVTQLHTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.7 1 NLLAQVTQLYTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.8 1 NLLDQVTQLYTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.9 1 NLLDQVTQLYTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.10 1 NLLNQVTQLYAKHNSNHQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.11 1 NLLDQVTQLYTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.12 8 NLLNQVTQLYTRHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.13 1 NLLDQVTQLYTKHNSNYQLYTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.14 1 NLLDQVTQLYTKHNSNYQQYNAQAGTLDLRQKAEYLKGLNDWAERLLQEL
M3.15 2 NLLDQVTQLYTKHNSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
M3.16 1 NLLDQVTQLYTKHNSNYQQYNAQDSNYQQYNAQAGRLDLRQKAEYLKGLNDWAERLLQEL
1102030
M5.0 1 AVTRGTINDPQRAKEALDKYELENHDLKTK
M5.6 6 TVTRGTINDPQRAKEALDKYELENHDLKTK
M5.7 1 TVTRGTINDPQRAKEALDKYELENHDLKTK
M5.8 1 TVTRGTINDPQRAKEALDKYELENHDLKTE
M5.10 1 TVTRSTINDPQRAKEALDKYELENHDLKTK
M5.13 2 VVTRSTINDPQRAKEALDKYELENHDLKTE
M5.14 27 TVTRGTINDPQRAKEALDKYELENHDLKTK
M5.18 2 TVTRGTVNDPQRAKEILDKYELENHDLKTK
M5.19 1 TVTGGTINDPQRAKEALDKYELENHDLKTK
M5.22 1 TVTRGTINDPQRAKAALDKYELENHDLKTK
a

The isolates were obtained from epidemiologic studies of invasive disease (9) and uncomplicated pharyngitis (12), yielding 1,066 and 2,060 isolates, respectively (total isolates = 3,126).

b

Boldface indicates amino acid substitution compared to the vaccine sequence.