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. 2025 Feb 6;5(1):e31. doi: 10.1017/ash.2024.441

Table 3.

Antimicrobial regimens prescribed

Dosing Regimens Utilized Success (n = 100) Failure (n = 100) Total (n = 200) Appropriately dosed*
Monotherapy Regimens
Amoxicillin-clavulanate 875 mg twice daily 4 1 5 X
Cefuroxime 500 mg three times daily 0 1 1 X
Cephalexin 500 mg twice daily 5 8 13
Cephalexin 1000 mg twice daily 2 2 4
Cephalexin 500 mg three times daily 7 6 13
Cephalexin 1000 mg three times daily 0 3 3 X
Cephalexin 500 mg four times daily 18 9 27 X
Clindamycin 300 mg twice daily 0 2 2
Clindamycin 150 mg three times daily 0 1 1
Clindamycin 300 mg three times daily 1 4 5
Clindamycin 300 mg four times daily 1 3 4 X
Clindamycin 450 mg three times daily 3 4 7 X
Doxycycline 100 mg twice daily 28 20 47 X
SMX/TMP 1 DS tablet twice daily 18 17 36
SMX/TMP 2 DS tablets twice daily 3 5 8 X
Dual Therapy Regimens
Amoxicillin-clavulanate 875 mg twice daily & doxycycline 100 mg twice daily 0 1 1 X
Amoxicillin-clavulanate 875 mg twice daily & SMX/TMP 1 DS tablet twice daily 0 1 1
Cephalexin 500 mg twice daily & doxycycline 100 mg twice daily 0 1 1
Cephalexin 500 mg four times daily & doxycycline 100 mg twice daily 2 0 2 X
Cephalexin 1000 mg two times daily & doxycycline 100 mg twice daily 0 1 1
Cephalexin 500 mg twice daily & SMX/TMP 1 DS tablet twice daily 0 1 1
Cephalexin 1000 mg twice daily & SMX/TMP 1 DS tablet twice daily 0 3 3
Cephalexin 500 mg three times daily & SMX/TMP 1 DS tablet twice daily 1 1 2
Cephalexin 500 mg four times daily & SMX/TMP 1 DS tablet twice daily 5 4 9
Cephalexin 1000 mg four times daily & SMX/TMP 1 DS tablet twice daily 0 1 1
Doxycycline 100 mg twice daily & SMX/TMP 1 DS tablet twice daily 2 0 2
*

Appropriately dosed defined as meeting minimum dosing recommendation in Table 1.