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. 2024 Dec 31;69(2):e01448-24. doi: 10.1128/aac.01448-24

Fig 2.

Graph compares rectal temperatures of three groups of sheep over 14 days post-infection: T. gondii-infected and treated, G1; infected and untreated, G2; non-infected sheep, G3 over 14 days. G1 displays reduced fever compared to G2.

Rectal temperatures of T. gondii-infected and uninfected sheep, receiving or not receiving the treatment with BKI-1748. Each point represents the mean + SD for each group. Horizontal dashed line indicates the upper threshold for physiological rectal temperature in sheep, and the black arrow points the beginning of the treatment on day 7 p.i. For significant differences between infected groups, (****) indicates P < 0.0001.