Table 2.

Gene set enrichment analysis of the HAG network in different human lung adenocarcinoma cohorts

GEO ID	Cohort description	Experimental groups	Enrichment analysis (adjusted P value)
			HAG	PER	Thiol	SOD
GSE21933	21 tumor tissues and adjacent normal tissue	Tumor versus normal tissue	0.335	0.022*	0.781	0.096
GSE41271	269 lung cancer specimens	Advanced versus early stagesa	0.030*	0.538	0.016*	0.032*
GSE42127	174 lung cancer specimens with clinicopathological information	Dead versus alive	0.014*	0.502	0.005**	0.772

Transcript profiles of human lung adenocarcinoma patients were obtained from GEO. Nominal P value of enrichment analysis obtained from GSEA (P < 0.05)

HAG human antioxidant gene network, PER peroxidase gene set, Thiol thiol-containing gene set, SOD superoxide dismutase gene set

^aPatients were grouped as early (I–II) or advanced (III–IV) clinical stages