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. 2014 Mar 15;140(5):789–800. doi: 10.1007/s00432-014-1632-4

Table 2.

Patient and tumour characteristics by level of hospital care (1998–2012, n = 8,601)

Level of hospital care University hospital Level III
hospital
Level II
hospital
Level I
hospital
Speciality
hospital
Hospital
n.a.
Total p value
n = 1,990 n = 1,710 n = 2,032 n = 2,281 n = 343 n = 245 n = 8,601
Prognostic factors n (%)a n (%)a n (%)a n (%)a n (%)a n (%)a n (%)a
Age
mean ± SD 65.7 ±12.6 71.2 ±12.5 72.2 ±12.3 74.5 ±11.6 73.8 ±12.2 76.0 ±12.1 71.3 ±12.7 <.0001
Age in classes
<50 years 240 (12.1) 104 (6.1) 115 (5.7) 94 (4.1) 13 (3.8) 11 (4.5) 577 (6.7) <.0001
50–59 years 367 (18.4) 221 (12.9) 204 (10.0) 169 (7.4) 38 (11.1) 15 (6.1) 1,014 (11.8)
60–69 years 583 (29.3) 373 (21.8) 448 (22.1) 414 (18.2) 70 (20.4) 41 (16.7) 1,929 (22.4)
70–79 years 581 (29.2) 568 (33.2) 660 (32.5) 789 (34.6) 103 (30.0) 70 (28.6) 2,771 (32.2)
≥80 years 219 (11.0) 444 (26.0) 605 (29.8) 815 (35.7) 119 (34.7) 108 (44.1) 2,310 (26.9)
Sex
Male 1,278 (64.2) 947 (55.4) 1,123 (55.3) 1,221 (53.5) 186 (54.2) 134 (54.7) 4,889 (56.8) <.0001
Female 712 (35.8) 763 (44.6) 909 (44.7) 1,060 (46.5) 157 (45.8) 111 (45.3) 712 (35.8)
T Category (comb.)
T1 317 (20.1) 325 (27.7) 347 (25.0) 316 (23.0) 40 (23.4) 19 (30.2) 1,364 (23.7) <.0001
T2 438 (27.7) 397 (33.9) 494 (35.5) 458 (33.4) 53 (31.0) 20 (31.8) 1,860 (32.4)
T3 692 (43.8) 330 (28.2) 357 (25.7) 392 (28.6) 55 (32.2) 15 (22.8) 1,841 (32.0)
T4 133 (8.4) 120 (10.2) 192 (13.8) 207 (15.1) 23 (13.5) 9 (14.3) 684 (11.9)
Not available 410 (20.6) 538 (31.5) 642 (31.6) 908 (39.8) 172 (50.2) 182 (74.3) 2,852 (33.2)
N Category (comb.)
N0 593 (36.8) 439 (37.1) 533 (37.3) 540 (37.8) 57 (32.2) 27 (47.4) 2,189 (37.2) <.0001
N+ 967 (60.0) 664 (56.1) 822 (57.6) 772 (54.1) 107 (60.5) 27 (47.4) 3,359 (57.1)
NX 53 (3.3) 81 (6.8) 73 (5.1) 114 (8.0) 13 (7.3) 3 (5.3) 337 (5.7)
Not available 377 (18.9) 526 (30.8) 604 (29.7) 855 (37.5) 166 (48.4) 188 (76.7) 2,716 (31.6)
M Category (primary)
M1 571 (28.7) 461 (27.0) 533 (26.2) 555 (24.3) 97 (28.3) 41 (16.7) 2,258 (26.3) 0.0003
Grade
G1 55 (2.3) 67 (4.2) 129 (6.9) 100 (4.7) 18 (6.3) 15 (7.7) 384 (4.8) <.0001
G2 403 (21.2) 472 (29.8) 529 (28.3) 609 (28.8) 72 (25.3) 82 (42.3) 2,167 (27.3)
G3/4 1,442 (75.9) 1,047 (66.0) 1,213 (64.8) 1,404 (66.5) 195 (68.4) 97 (50.0) 5,398 (67.9)
Not available 90 (4.5) 124 (7.3) 161 (7.9) 168 (7.4) 58 (16.9) 51 (20.8) 652 (7.6)
Lauren classification
Intestinal 869 (55.2) 774 (59.4) 904 (59.5) 1,085 (61.0) 146 (64.9) 90 (64.8) 3,868 (59.2) <.0001
Diffuse 601 (38.2) 484 (37.1) 569 (37.5) 639 (35.9) 73 (32.4) 44 (31.7) 2,410 (36.9)
Mixed 103 (6.6) 46 (3.5) 46 (3.0) 54 (3.0) 6 (2.7) 5 (3.6) 260 (4.0)
Not available 417 (20.1) 406 (23.7) 513 (25.3) 503 (22.1) 118 (34.4) 106 (43.3) 2,063 (24.0)
Histology
Adenocarcinoma 1,362 (69.4) 1,220 (72.6) 1,454 (72.9) 1,691 (75.5) 263 (80.2) 178 (78.4) 6,168 (73.2) <.0001
Signet cell carcinoma 550 (28.0) 425 (25.3) 489 (24.5) 482 (21.5) 55 (16.8) 41 (18.1) 2,042 (24.2)
Other carcinoma 51 (2.6) 35 (2.1) 51 (2.6) 66 (3.0) 10 (3.1) 8 (3.5) 221 (2.6)
Not available 27 (1.4) 30 (1.8) 38 (1.9) 42 (1.8) 15 (4.4) 18 (7.4) 170 (2.0)
Location of primary tumour
GEJ, Cardia 665 (36.4) 287 (18.8) 355 (20.1) 363 (18.3) 65 (24.0) 49 (30.4) 1,784 (23.7) <.0001
Corpus, others 769 (42.1) 731 (47.9) 824 (46.7) 905 (45.7) 127 (46.9) 66 (41.0) 3,422 (45.4)
Antrum, Pylorus 391 (21.4) 508 (33.3) 586 (33.2) 714 (36.0) 79 (29.2) 46 (28.6) 2,324 (30.9)
Not available 165 (8.3) 184 (10.8) 267 (13.1) 299 (13.1) 72 (21.0) 84 (34.3) 1,071 (12.5)
Total 1,990 (100) 1,710 (100) 2,032 (100) 2,281 (100) 343 (100) 245 (100) 8,601 (100)

n.a., not available; SD, standard deviation; comb., combined cT/pT or cN/pN; GEJ, gastro-oesophageal junction

a Missing values were excluded from calculations of frequency distribution; column percentage can differ slightly from 100 % due to rounding