Table 1. Crossing over requires linear element component Rec10 and sister chromatid cohesins Rec8 and Rec11.
Nominal cM*
|
rec+
|
rec10Δ
|
rec8Δ
|
rec11Δ
|
|||||
---|---|---|---|---|---|---|---|---|---|
Chr. | Interval | cM† | cM | Red'n‡ | cM | Red'n | cM | Red'n | |
I | lys3-ura1 | 34 | 25 | 0.2 | 120 | 2.5 | 10 | 1.8 | 14 |
I | ura1-pro1 | 42 | 27 | 0.5 | 50 | 5.9 | 4.6 | 4.0 | 6.8 |
I | lys3-pro1 | 76 | 57 | 0.7 | 80 | 6.7 | 8.5 | 6.3 | 9.0 |
I | ura1-lys7 | 601 | —§ | 1.1 | 600 | 31 | 20 | 76 | 7.9 |
II | pat1-leu1 | 47 | 58 | ND | ND | 2.2 | 26 | ND | ND |
II | lys4-his4 | 12 | 15 | 0.2 | 75 | 1.6 | 9.4 | 2.7 | 5.6 |
II | his4-arg4 | 74 | 53 | 1.2 | 44 | 8.2 | 6.5 | 15 | 3.5 |
II | arg4-trp1 | 54 | 47 | ND | ND | 2.6 | 18 | 2.1 | 22 |
III | ura4-ade6 | 197 | — | 1.1 | 180 | 2.2 | 90 | 6.5 | 30 |
III | ade6-arg1 | 47 | 73 | <0.4 | >180 | 0.8 | 90 | 0.7 | 100 |
III | arg1-ade5 | 128 | — | ND | ND | 4.1 | 31 | 8.2 | 16 |
III | ura4-arg1 | 244 | — | 0.8 | >300 | 5.0 | 49 | 11.1 | 22 |
III | ura4-ade5 | 372 | — | ND | ND | 9.4 | 40 | 22.2 | 17 |
ND, not determined; Red'n, reduction.
Calculated from the observed recombinant frequency (Table 4) and Haldane's mapping function: x = −50 ln(1-2R), where x = genetic distance in centimorgans (cM) and R = fraction of recombinant spores among total spores analyzed.
Factor by which the observed genetic distance in the indicated mutant is less than that observed in wild type or, for values >75 cM, the nominal distance.
Observed recombinant frequency too close to 50% for reliable calculation of genetic distance.