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. 2005 Jul 25;102(31):10837–10840. doi: 10.1073/pnas.0504820102

Fig. 4.

Fig. 4.

Free energies of trajectories, Inline graphic, for different values of the parameter b. The curve for b = 1 is that of Fig. 1 Left, with T = 1, N = 16c-1, and tobs = 320. The curves with b = 1.001, 1.002, and 1.003 are obtained by adding Inline graphic to the b = 1 curve. Triangles show the free energy computed by simulation at b = 1.001 using transition path sampling combined with free energy perturbation theory.