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. 2025 Feb 13;25:257. doi: 10.1186/s12885-025-13638-7

Table 2.

Comparative analysis of patient characteristics and menopausal status according body mass index (kg/m2 ) status of studied patients

BMI<25 kg/m2 25.0≤BMI< 30.0 kg/m2 BMI≥30 kg/m2
Pre menopausal Post menopausal P value Pre menopausal Post menopausal P value Pre menopausal Post menopausal P-value
Mean age (SD) 47.57 (8.27) 66.12 (9.36) 49.31 (7.86) 65.29 (8.855) 50.62 (7.56) 64.67 (8.28)
Surgery Type
 Quadrantectomy (BCS) 664 (57.7%) 436 (49.1%) <0.001 991 (61.4%) 849 (58.2%) <0.001* 585 (61.4%) 718 (62.7%) 0.06
 Mastectomy 417 (36.1%) 417 (46.9%) 508 (31.4%) 553 (37.9%) 304 (31.9%) 374 (32.6%)
 Quadrantectomy (BCS) ,then Mastectomy 69 (6.0%) 28 (3.1%) 111 (6.9%) 49 (3.4%) 111 (6.9%) 49 (3.4%)
Stage
 1 242 (33.5%) 158 (31.7%) 0.16 313 (29.4%) 267 (30.8%) 0.17 192 (29.4%) 184 (26.9%) 0.51
 2 427 (59.1%) 288 (57.8%) 655 (61.6%) 503 (58.1%) 392 (60.1%) 420 (61.4%)
 3 53 (7.3%) 52 (10.4%) 95 (8.9%) 96 (11.1%) 68 (10.4%) 80 (11.7%)
Permanent Pathology Multifocal
 No 1049 (91.2%) 833 (94.6%) 0.004 1479 (91.9%) 1387 (95.7%) <0.001 867 (91.4%) 1070 (94.1%) 0.01
 Yes 101 (8.8%) 48 (5.4%) 867 (8.1%) 1070 (4.3%) 82 (8.6%) 67 (5.9%)
Permanent Pathology Tumor Grade
 1 174 (16.7%) 184 (23.1%) <0.001 232 (15.7%) 255 (19.5%) 0.01 149 (17.3%) 185 (17.8%) 0.01
 2 638 (61.3%) 480 (60.2%) 921 (62.5%) 806 (61.7%) 491 (57.0%) 645 (62.2%)
 3 228 (21.9%) 134 (16.8%) 321 (21.8%) 246 (18.8%) 222 (25.8%) 207 (20.0%)
Invasion
 Non 587 (51.0 %) 414 (47.0 %) 0.06 756 (47%) 626 (43.2) 0.03 439 (46.3%) 499 (43.9%) 0.3
 Vascular 271 (23.6 %) 217 (24.6 %) 392 (24.3%) 406 (28.0%) 239 (25.2%) 315 (27.7%)
 Preneural 75 (6.5 %) 76 (8.6 %) 120 (7.5%) 110 (7.6%) 68 (7.2%) 80 (7.0%)
 Both of them 178 (15.5 %) 155 (17.6 %) 290 (18.0%) 278 (19.2%) 170 (17.9%) 217 (19.1%)
 Lymphatic , Vascular 39 (3.4 %) 19 (2.2 %) 52 (3.2%) 30 (2.1%) 33 (3.5%) 26 (2.3%)
Axillary Type
 ALND at first 488 (42.7%) 403 (47.5%) 0.07 660 (41.3%) 678 (47.8%) 0.002 381 (40.5%) 442 (39.9%) 0.56
 SLNB 458 (40.1%) 323 (38.0%) 682 (42.7%) 543 (38.3%) 151 (16.0%) 162 (14.6%)
 SLNB then ALND 197 (17.2%) 123 (14.5%) 255 (16.0%) 198 (14.0%) 409 (43.5%) 503 (45.4%)
Hormone receptor
 Luminal A 564 (49.0%) 406 (46.1%) <0.001 772 (48.0%) 717 (49.4%) <0.001 449 (47.3%) 579 (50.9%) 0.007
 Luminal B 211 (18.3%) 129 (14.6%) 288 (17.9%) 187 (12.9%) 142 (15.0%) 149 (13.1%)
 Her2 80 (7.0%) 71 (8.1%) 143 (8.9%) 135 (9.3%) 102 (10.7%) 81 (7.1%)
 Triple Negative 130 (11.3%) 88 (10.0%) 172 (10.7%) 110 (7.6%) 106 (11.2%) 113 (9.9%)
Preoperative Chemotherapy
 No 892 (77.6%) 753 (85.5%) <0.001 1300 (80.7%) 1248 (86.1%) <0.001 776 (81.8%) 976 (85.8%) 0.01
 Yes 258 (22.4%) 128 (14.5%) 310 (19.3%) 202 (13.9%) 173 (18.2%) 161 (14.2%)
Postoperative Chemotherapy
 No 154 (13.4%) 152 (17.3%) 0.01 185 (11.5%) 228 (15.7%) <0.001 106 (11.2%) 164 (14.4%) 0.01
 Yes 996 (86.6%) 729 (82.7%) 1425 (88.5%) 1222 (84.3%) 843 (88.8%) 973 (85.6%)
Radiotherapy postoperative
 No 324 (36.8%) 204 (17.7%) <0.001 410 (28.3%) 280 (17.4%) <0.001 272 (23.9%) 162 (17.1%) <0.001
 Yes 557 (63.2%) 946 (82.3%) 1040 (71.7%0 1330 (82.6%) 865 (76.1%) 787 (82.9%)
Hormone therapy
 No 278 (24.2%) 211(24.0%) 0.9 392 (24.3%) 328 (22.6%) 0.26 268 (28.2%) 261 (23.0%) 0.006
 Yes 872 (75.8%) 670 (76.0%) 1218 (75.7%) 1122 (77.4%) 681 (71.8%) 876 (77.0%)