Table 4. Survival data stratified by event type and grade.

	Grade 1 or 2			Grade 3 or 4
	CNS NAE (n = 12)	PNS NAE (n = 17)	Other irAE (n = 712)	CNS NAE (n = 11)	PNS NAE (n = 14)	Other irAE (n = 410)	None (n = 1961)
Time ICI to irAE (months)	1.1 (0.7, 4.7)	2 (0.9, 4.2)	2.5 (0.9, 5.7)	1.8 (1.2, 3.3)	1.5 (0.7, 9.3)	1.6 (0.7, 4.2)	NA

Continuous variables reported as median [IQR].

CNS: Central nervous system; irAE: Immune-related adverse event; ICI: Immune checkpoint inhibitor; NAE: Neurological adverse event; PNS: Peripheral nervous system.