Figure 1:

Upregulation of PLK1 in Lung Cancer and Inhibition of Cell Proliferation by Silencing PLK1. (a) Analysis of PLK1 expression levels in lung cancer. (b) Correlation analysis between PLK1 expression and prognosis of lung cancer patients. (c-e) Validation of si-PLK1 transfection efficiency. (f and g) Inhibition of lung cancer cell proliferation by silencing PLK1. (h and i) Inhibition of clonogenic capacity in lung cancer cells by silencing PLK1. n = 3. (^*P < 0.05, ^✶✶P < 0.01, ^✶✶✶P < 0.001). PLK1: Polo-like kinase 1, si-NC: negative control to PLK1 siRNA, si-PLK1: PLK1 siRNA.