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Up-regulation of PTEN promotes autophagy and inhibits the proliferation of lung cancer cells. (a and b) Detection of ROS levels in cells. (c and d) Promotion of autophagy-related protein expression in lung cancer cells. (e) Accumulation of autophagosomes in lung cancer cells. (f and g) Dose-dependent inhibition of lung cancer cell proliferation. (h and i) Dose-dependent inhibition of clonogenic capacity in lung cancer cells. n=3 (✶P < 0.05, ✶✶ P < 0.01, ✶✶✶ P < 0.001).
