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. 2025 Feb 3;12:1486917. doi: 10.3389/fnut.2025.1486917

Table 2.

The correlation between clinical characteristics and cognitive impairment.

Characteristics Statistics OR (95% CI) p-value
Age (years) 58.86 ± 8.93 1.063 (1.056, 1.070) <0.001
Sex
Female 3,522 (49.29%) Reference
Male 3,623 (50.71%) 0.535 (0.475, 0.602) <0.001
Residence
City 2,668 (37.34%) Reference
Rural 4,477 (62.66%) 2.009 (1.765, 2.288) <0.001
Education
Below primary school 2,979 (41.69%) Reference
Primary school 1,705 (23.86%) 0.249 (0.212, 0.292) <0.001
Middle school 1,633 (22.86%) 0.100 (0.080, 0.125) <0.001
High school and above 828 (11.59%) 0.057 (0.038, 0.084) <0.001
Marital status
Others 769 (10.76%) Reference
Married and cohabiting 6,376 (89.24%) 0.516 (0.438, 0.609) <0.001
Retirement
No 6,275 (87.82%) Reference
Yes 870 (12.18%) 0.315 (0.246, 0.405) <0.001
Current smoking
No 4,831 (67.61%) Reference
Yes 2,313 (32.37%) 0.773 (0.681, 0.878) <0.001
Current drinking
No 4,632 (64.83%) Reference
Yes 2,513 (35.17%) 0.728 (0.643, 0.825) <0.001
Socializing
No 3,340 (46.75%) Reference
Yes 3,805 (53.25%) 0.531 (0.472, 0.597) <0.001
Hypertension
No 3,741 (52.36%) Reference
Yes 3,404 (47.64%) 1.293 (1.152, 1.452) <0.001
Diabetes
No 6,081 (85.11%) Reference
Yes 1,064 (14.89%) 1.028 (0.875, 1.208) 0.736
Dyslipidemia
No 6,410 (89.71%) Reference
Yes 735 (10.29%) 0.753 (0.614, 0.924) 0.007
Stroke
No 6,980 (97.69%) Reference
Yes 165 (2.31%) 1.139 (0.786, 1.650) 0.491
Depressive symptoms
No 4,613 (64.56%) Reference
Yes 2,532 (35.44%) 2.136 (1.900, 2.402) <0.001
SBP (mmHg) 129.29 ± 21.16 1.010 (1.007, 1.013) <0.001
DBP (mmHg) 75.52 ± 12.15 0.998 (0.993, 1.003) 0.357
BMI (kg/m2) 23.63 ± 3.85 0.937 (0.922, 0.953) <0.001
FPG (mg/dL) 102.42 (94.50, 113.58) 1.000 (0.998, 1.001) 0.846
TC (mg/dL) 193.56 ± 37.68 1.000 (0.998, 1.001) 0.950
TG (mg/dL) 106.20 (75.23, 154.88) 0.999 (0.998, 1.000) 0.001
LDL-C (mg/dL) 116.60 ± 34.69 1.000 (0.998, 1.001) 0.561
HDL-C (mg/dL) 50.97 ± 15.14 1.009 (1.006, 1.013) <0.001
hsCRP (mg/L) 1.03 (0.55, 2.14) 1.008 (1.001, 1.015) 0.017
TCBIa 3.09 ± 0.31 0.488 (0.401, 0.594) <0.001

BMI, body mass index; CI, confidence interval; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; hsCRP, high-sensitivity C-reactive protein; LDL-C, low-density lipoprotein cholesterol; OR, odds ratio; SBP, systolic blood pressure; TC, total cholesterol; TCBI, triglycerides, total cholesterol, and body weight index; TG, triglyceride.

a

The TCBI value underwent a log transformation in univariate analysis.