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. 2025 Feb 3;12:1486917. doi: 10.3389/fnut.2025.1486917

Table 3.

Association between TCBI and cognitive impairment.

TCBIa OR (95% CI), p
Model 1 Model 2 Model 3
TCBI 0.488 (0.401, 0.594) <0.001 0.508 (0.412, 0.625) <0.001 0.703 (0.529, 0.933) 0.015
TCBI quartile [median (range)]
Q1 [2.75 (<2.87)] Reference Reference Reference
Q2 [2.98 (2.87–3.06)] 0.702 (0.599, 0.821) <0.001 0.698 (0.592, 0.823) <0.001 0.801 (0.667, 0.962) 0.018
Q3 [3.17 (3.07–3.28)] 0.693 (0.592, 0.812) <0.001 0.669 (0.567, 0.798) <0.001 0.837 (0.684, 1.024) 0.084
Q4 [3.45 (≥3.29)] 0.562 (0.477, 0.662) <0.001 0.573 (0.483, 0.681) <0.001 0.771 (0.612, 0.972) 0.028
p for trend <0.001 <0.001 0.043

CI, confidence interval; OR, odds ratio; TCBI, triglycerides, total cholesterol, and body weight index. Model 1 was unadjusted. Model 2 was adjusted for age and sex. Model 3 was adjusted for age, sex, residence, education, marital status, retirement, current smoking, current drinking, socializing, hypertension, diabetes, dyslipidemia, stroke, depression symptoms, SBP, DBP, BMI, FPG, LDL-C, HDL-C, and hsCRP.

a

The TCBI value underwent a log transformation.