Table 4.
The effect size of TCBI on cognitive impairment in the subgroup.
| Characteristics | N | OR (95% CI), p-value | p for interaction |
|---|---|---|---|
| Age (years) | 0.026 | ||
| 45–60 | 4,001 | 0.716 (0.480, 1.066) 0.100 | |
| ≥60 | 3,144 | 0.655 (0.438, 0.979) 0.039 | |
| Sex | 0.480 | ||
| Male | 3,623 | 0.529 (0.343, 0.818) 0.004 | |
| Female | 3,522 | 0.885 (0.602, 1.301) 0.535 | |
| BMI (kg/m2) | 0.294 | ||
| <24 | 4,148 | 0.812 (0.567, 1.164) 0.257 | |
| ≥24 | 2,997 | 0.516 (0.329, 0.811) 0.004 | |
| Residence | 0.546 | ||
| City | 2,668 | 1.072 (0.621, 1.852) 0.802 | |
| Rural | 4,477 | 0.613 (0.439, 0.856) 0.004 | |
| Education | 0.450 | ||
| Illiteracy | 2,979 | 0.679 (0.482, 0.957) 0.027 | |
| Primary school | 1,705 | 0.840 (0.431, 1.639) 0.610 | |
| Middle school | 1,633 | 0.658 (0.255, 1.696) 0.386 | |
| High school and above | 828 | 0.591 (0.127, 2.752) 0.503 | |
| Marital status | 0.796 | ||
| Married and cohabiting | 6,376 | 0.783 (0.577, 1.062) 0.116 | |
| Others | 769 | 0.279 (0.123, 0.636) 0.002 | |
| Retirement | 0.778 | ||
| No | 6,275 | 0.694 (0.518, 0.930) 0.015 | |
| Yes | 870 | 0.678 (0.202, 2.268) 0.528 | |
| Current smoking | 0.710 | ||
| No | 4,831 | 0.768 (0.545, 1.081) 0.130 | |
| Yes | 2,313 | 0.556 (0.330, 0.938) 0.028 | |
| Current drinking | 0.034 | ||
| No | 4,632 | 0.643 (0.451, 0.917) 0.015 | |
| Yes | 2,513 | 0.783 (0.484, 1.266) 0.318 | |
| Socializing | 0.010 | ||
| No | 3,340 | 0.810 (0.552, 1.190) 0.283 | |
| Yes | 3,805 | 0.568 (0.371, 0.871) 0.009 | |
| Hypertension | 0.326 | ||
| No | 3,741 | 0.714 (0.470, 1.084) 0.114 | |
| Yes | 3,404 | 0.681 (0.460, 1.007) 0.054 | |
| Diabetes | 0.794 | ||
| No | 6,081 | 0.707 (0.511, 0.979) 0.037 | |
| Yes | 1,064 | 0.475 (0.249, 0.906) 0.024 | |
| Dyslipidemia | 0.684 | ||
| No | 6,410 | 0.700 (0.520, 0.943) 0.019 | |
| Yes | 735 | 0.840 (0.311, 2.267) 0.730 | |
| Stroke | 0.942 | ||
| No | 6,980 | 0.702 (0.526, 0.936) 0.016 | |
| Yes | 165 | 0.633 (0.090, 4.450) 0.646 | |
| Depressive symptoms | 0.648 | ||
| No | 4,613 | 0.627 (0.428, 0.918) 0.017 | |
| Yes | 2,532 | 0.814 (0.532, 1.248) 0.346 |
CI, confidence interval; OR, odds ratio; BMI, body mass index. Above models were adjusted for age, sex, residence, education, marital status, retirement, current smoking, current drinking, socializing, hypertension, diabetes, dyslipidemia, stroke, depression symptoms, SBP, DBP, BMI, FPG, LDL-C, HDL-C, and hsCRP. In each case, the model was not adjusted for the stratification variable. The TCBI value underwent a log transformation.