Table 2.

TJ protein families and their representatives.

Protein family	Protein	Localization in nervous system
Claudins	Claudin-3	Brain endothelium (Wolburg et al., 2003) Oli-neu cells (a model of oligodendroglial studies) (Chen Y. et al., 2021)
	Claudin-5	Brain endothelium (Hashimoto et al., 2023)
	Claudin-11	CNS myelin/oligodendrocytes (Bronstein et al., 2000; Gjervan et al., 2024)
	Claudin-12	Brain endothelium (Vanlandewijck et al., 2018; Garcia et al., 2022) Oligodendrocytes, astrocytes, neurons (Castro Dias et al., 2019)
	Claudin-25	Brain endothelium Oligodendrocytes (Vanlandewijck et al., 2018; Garcia et al., 2022)
TAMP family [tight junction- associated MARVEL (MAL and related proteins for vesicle trafficking and membrane link) protein]	Occludin	Brain endothelium pericytes Astrocytes (Castro et al., 2018) Neurons (Bauer et al., 1999)
	Tricellulin (MARVEL D2)	Brain endothelium (Iwamoto et al., 2014) Astrocytes neurons (Mariano et al., 2013) Microglia (Kojima et al., 2013)
	MARVEL D3	Brain endothelium (Tornabene et al., 2019)
ZO	Zonula occudens – 1, −2, −3	Brain endothelium (Gray et al., 2019) Astrocytes (Morgan, 2016)
JAMs	Junctional Adhesion Molecules	Brain endothelium (Kakogiannos et al., 2020)
Cingulin		Brain endothelium (Schossleitner et al., 2016)