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. 2025 Jan 31;22(12):995–1002. doi: 10.18502/ijrm.v22i12.18065

Table 2.

The effects of dienogest and GnRH agonist on different aspects of endometriosis before and after treatment

Variables Dienogest GnRH agonist
Before After P-value Before After P-value
Dysmenorrhea* 7.981 ± 2.356 3.654 ± 2.457 < 0.0001 8.115 ± 1.916 3.442 ± 2.461 < 0.0001
Dyspareunia** 5.500 (3.250–8.000) 2.000 (0.000–4.000) < 0.0001 5.000 (3.000–7.000) 0.000 (0.000–4.000) < 0.0001
Dyschezia** 3.000 (0.000–7.000) 2.000 (0.000–4.000) < 0.0001 3.000 (0.000–8.000) 2.000 (0.000–6.000) < 0.0001
Irregular vaginal bleeding*** 22 (42.31) 6 (11.54) 0.0007 20 (38.46) 4 (7.69) 0.0003
*Data presented as Mean ± SD, Wilcoxon matched-pairs signed rank test. **Data presented as Median (IQR), Wilcoxon matched-pairs signed rank test. ***Data presented as n (%), Fisher's exact test. GnRH: Gonadotropin-releasing hormone agonist