Figure 2.

DPP-8/9 activity in RAW264.7 cell lysates on the 2^nd, 4^th, 6^th, 8th, and 10^th day with and without DPP inhibitors. RAW264.7 cell lysate with 50 µg/ml of RANKL and 20 ng/ml of LPS was used as the negative control for the DPP-8/9 assay. All values are presented as the mean ± SEM (n=3). Statistical significance was determined by one-way ANOVA with Tukey’s multiple comparison test. #P<0.05 and ##P<0.01 and ###P<0.001, when compared with the control group (group I), *P<0.05, and **P<0.01, when compared vs RANKL+LPS group (group II).