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MEL exerted anti-PF effects by regulating the TGF-β1/Smad2/3 and AMPK/SIRT1/PGC-1α signaling pathways
Images of immunohistochemical staining for TGF-β1 and evaluation of positive TGF-β1 expression (A) in tissues. The levels of proteins associated with the TGF-β1/Smad2/3 (B-E) and AMPK/SIRT1/PGC-1α (F-I) signaling pathways were measured by WB. The data are shown as the mean ± SD (n =3). *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.
MEL: Melittin; PF: Pulmonary fibrosis
