Table 3.
Disease burden in 2021 and rate change in age-standardized rates from 1990 to 2021 by cause of CKD
| Characteristics | Prevalence (95% uncertainty interval) | Incidence (95% uncertainty interval) | Mortality (95% uncertainty interval) | DALYs (95% uncertainty interval) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Counts (2021) |
Age-standardized rates per 100,000 (2021) |
Rate change in age-standardized rates, 1990–2021 |
Counts (2021) |
Age-standardized rates per 100,000 (2021) |
Rate change in age-standardized rates, 1990–2021 |
Counts (2021) |
Age-standardized rates per 100,000 (2021) |
Rate change in age-standardized rates, 1990–2021 |
Counts (2021) |
Age-standardized rates per 100,000 (2021) |
Rate change in age-standardized rates, 1990–2021 |
|
| CKD due to T1DM | 6,295,710 (5,459,693–7,114,345) | 77.31 (66.91–87.58) | 0.34 (0.25–0.43) | 95,140 (82,237–111,471) | 1.31 (1.12–1.55) | 0.19 (0.08–0.31) | 94,020 (71,457–119,984) | 1.08 (0.83–1.38) | 0.003 (−0.14 to 0.11) | 3,875,628 (3,062,396–4,845,503) | 45.20 (36.01–56.35) | −0.04 (−0.17 to 0.17) |
| CKD due to T2DM | 107,559,955 (99,170,797- 115,994,732) | 1259.63 (1161.99- 1359.92) | −0.05 (−0.07 to −0.03) | 2,012,025 (1,857,800–2,154,288) | 23.07 (21.40–24.72) | 0.21 (0.15–0.27) | 477,273 (401,541–565,951) | 5.72 (4.83–6.79) | 0.38 (0.19–0.50) | 11,278,935 (9,682,785–13,103,871) | 131.08 (112.75–152.49) | 0.24 (0.09–0.33) |
| CKD due to hypertension | 24,467,653 (22,861,634–26,230,869) | 291.19 (272.49–311.88) | −0.06 (−0.08 to −0.05) | 1,282,205 (1,195,230- 1,366,296) | 14.97 (14.02- 15.93) | 0.22 (0.17–0.28) | 454,359 (381,290- 524,688) | 5.54 (4.68- 6.41) | 0.29 (0.12–0.40) | 10,850,728 (9,207,080- 12,320,650) | 128.41 (109.14- 145.64) | 0.19 (0.04–0.28) |
| CKD due to glomerulonephritis | 10,735,809 (9,925,500- 11,520,171) | 129.94 (120.25- 139.51) | 0.01 (−0.01 to 0.03) | 357,288 (329,226- 388,483) | 4.84 (4.42–5.29) | 0.13 (0.08–0.18) | 193,997 (162,332- 226,569) | 2.34 (1.96–2.74) | 0.16 (0.07–0.25) | 6,959,758 (6,018,414- 7,961,673) | 84.47 (73.20- 96.13) | 0.09 (0.00–0.17) |
| CKD due to other and unspecified causes | 524,663,971 (488,899,870- 562,780,408) | 6247.94 (5823.88- 6691.38) | −0.00 (−0.01 to 0.01) | 16,188,381 (15,192,359- 17,180,106) | 189.36 (178.21- 200.61) | 0.22 (0.17–0.27) | 307,990 (357,326- 259,417) | 3.81 (3.20–4.41) | 0.15 (0.03–0.24) | 11,488,636 (10,007,838- 13,046,210) | 140.45 (122.56- 159.28) | −0.01 (−0.07 to 0.06) |
Data in parentheses represent the 95% uncertainty intervals. CKD chronic kidney disease. T1DM diabetes mellitus type 1. T2DM, diabetes mellitus type 2