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. 2025 Feb 17;14:43. doi: 10.1186/s13643-025-02789-0

Table 1.

Preliminary list of potential baseline variables and constructs [27]

Baseline data Example of the measurement
Primary outcome measures
 Pain intensity Visual Analogue Scale (VAS), Numeric Rating Scale (NRS), Northwick Park Neck Pain Questionnaire (NPQ)
 Pain-related disability Neck Disability Index (NDI), Neck Pain and Disability Scale (NPAD)
 Quality of life 36-Item Short Form Health Survey (SF-36), 12-Item Short Form Health Survey (SF-12), World Health Organisation Quality-of-Life Scale (WHOQOL-BREF), self-reported health outcomes (physical performance, functional ability, life satisfaction, overall cognitive functioning, etc.)
Demographic data of participants
 Age Present age
 Sex Male, female
 Body mass index (BMI) or height and weight Individual’s BMI or height and weight
 Occupation For the past year
Day-to-day life
 Leisure activities Sporting events, outdoor activities, and personal interests
 Physical health Physical fitness level
 Physical activity level Mild/moderate/vigorous
 Cigarette smoking Habits of smoking
 Alcohol use Drinking quantity/rate
 Computer use Hours per day
Socio-demographic features
 Economic and financial background Academic achievements, income
 Employability Workplace, job title, current work status
 Relationships Relationships with partners, relations, peers, and neighbours
 Healthiness Feeling well/lethargy levels
 Medication usage Medications used for current condition (chronic non-specific neck pain)
 Associated health problems Presenting other health-related conditions (e.g. other types of muscular pain except chronic non-specific neck pain, breathing difficulties, gastrointestinal problems, severe headaches, pain in more than one site of the body)
 Past trauma reported Medical leave (except for chronic non-specific neck pain), or traumatic incidents
Settlement and legal compensation
 Employee’s recompense; lost working hours, absence from regular work, paybacks, retirement fund Evidence of employee’s recompense, lost working hours/days, absence taken as a consequence of chronic non-specific neck pain, paybacks, applied or expect to apply for retirement fund
 Attribute to chronic non-specific neck pain Legal process, negligence for damage/harm, pain-inducing work, causes, and the rationale for chronic non-specific neck pain
Pre-existent chronic non-specific neck pain (affected prior to present incidence)
 Pain onset Onset of chronic non-specific neck pain (e.g., quick or continuing)
 Time length of the incidence Time length of chronic non-specific neck pain, duration concerning the incidence, and putting assertions
Clinical features of chronic non-specific neck pain at baseline
 Gravity of the discomfort due to chronic non-specific neck pain Pain rating scales, factors increasing or decreasing pain, tools, and questionnaires to assess pain severity, numeric rating scale
 Restrictions in the day-to-day activities Questionnaires and tools to assess the activity limitations, disability level, and participation restrictions
 Alteration of clinical features Recovering or deteriorating
Outcomes of the physical tests performed at baseline
 Joint movement ranges Change in range of motion
 Behaviour of the pain (central pain) Behaviour of the pain (on and off)
 Any different outcomes from other tests performed Muscle strength, endurance, flexibility, palpations, and attitudes of the limbs related to the body
Outcomes of the assessment of the nervous system at baseline
 Location; nerve root; radiculopathy Pain located in the neck region, radiating pain
Participant’s mental state
 Depression Questionnaires and tools to assess the condition
 Conditions that can affect the participant E.g. post-traumatic stress disorder, mood disorders, schizophrenia
Chronic non-specific neck pain findings
 Type and cause Detailed findings about type and causes (pain arising from muscles/ligaments/spinal joints, herniated disc, facet joint involvement)
 Participant’s ability to comprehend his/ her clinical features Participant’s ability to comprehend clinical features
Participant’s predictions regarding the improvement of the condition
 Self-assessed job readiness Self-assessed job readiness regarding chronic non-specific neck pain
 Self-evaluated job proficiency Self-assessment to continue the same work previously engaged, barriers, and capacity with chronic non-specific neck pain
 Psychological capability of returning to work Psychological capability to return to work, worker role interview
 Opportunities for returning to previous job Opportunities for returning to previous job
 Participant’s desire after treatments

Patient satisfaction

Self-reported treatment success

Minimal side effects