Table 2. Inhibition study of CDNB activity.
Inhibition (%) | |||||||
---|---|---|---|---|---|---|---|
Compound | Concentration (mM) | adGSTD5-5 | adGSTD1-1 | adGSTD2-2 | adGSTD3-3 | adGSTD4-4 | adGSTD6-6 |
Dichloroacetic acid | 0.5 | 16.84±3.22 | ND | ND | ND | ND | ND |
Cumene hydroperoxide | 2.5 | 37.17±1.19 | 30.36±9.53 | 60.44±2.15 | 28.94±4.82 | 29.53±3.77 | 28.27±2.56 |
p-Nitrobenzyl chloride | 1.0 | 33.40±6.07 | 43.38±5.17 | 37.60±3.67 | 55.36±1.84 | 49.77±1.35 | 9.52±1.98 |
p-Nitrophenyl bromide | 0.1 | 35.72±1.50 | 24.30±14.52 | 17.28±0.88 | 33.39±3.78 | 31.33±3.10 | 3.17±3.85 |
Ethacrynic acid | 0.1 | 84.67±0.71 | 100±0 | 99.57±0.59 | 98.31±0.10 | 100±0 | 86.36±1.65 |
0.01 | 55.22±0.66 | 99.46±1.54 | 94.88±1.32 | 81.61±0.76 | 85.49±1.58 | 57.73±3.09 | |
0.001 | 40.28±3.16 | 81.88±4.14 | 64.16±3.74 | 37.95±1.99 | 46.45±3.39 | 37.55±1.40 | |
S-Hexylglutathione | 0.1 | 71.98±1.76 | 94.93±0.65 | 97.08±0.92 | 67.84±1.10 | 76.91±0.26 | 64.14±3.58 |
0.01 | 24.87±3.93 | 63.18±3.21 | 75.44±0.61 | 32.07±1.58 | 20.09±1.24 | 35.03±2.46 | |
Permethrin | 0.01 | 35.56±1.68 | 20.37±1.90 | 27.36±5.45 | 35.87±1.87 | 47.73±3.08 | 11.70±1.87 |
Deltamethrin | 0.01 | 40.15±2.17 | 11.01±7.51 | 30.72±3.53 | 35.28±3.05 | 49.30±2.37 | 15.87±5.29 |
λCyhalothrin | 0.01 | 39.96±1.19 | 21.88±10.66 | 29.11±2.88 | 26.38±1.73 | 40.50±1.40 | 23.26±5.58 |