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. 2005 Jun 7;388(Pt 3):763–771. doi: 10.1042/BJ20042015

Table 2. Inhibition study of CDNB activity.

The CDNB activity was measured in the absence and presence of the respective compound at the concentration given. The data presented represent the means±S.D. for at least three independent experiments. ND, not detected.

Inhibition (%)
Compound Concentration (mM) adGSTD5-5 adGSTD1-1 adGSTD2-2 adGSTD3-3 adGSTD4-4 adGSTD6-6
Dichloroacetic acid 0.5 16.84±3.22 ND ND ND ND ND
Cumene hydroperoxide 2.5 37.17±1.19 30.36±9.53 60.44±2.15 28.94±4.82 29.53±3.77 28.27±2.56
p-Nitrobenzyl chloride 1.0 33.40±6.07 43.38±5.17 37.60±3.67 55.36±1.84 49.77±1.35 9.52±1.98
p-Nitrophenyl bromide 0.1 35.72±1.50 24.30±14.52 17.28±0.88 33.39±3.78 31.33±3.10 3.17±3.85
Ethacrynic acid 0.1 84.67±0.71 100±0 99.57±0.59 98.31±0.10 100±0 86.36±1.65
0.01 55.22±0.66 99.46±1.54 94.88±1.32 81.61±0.76 85.49±1.58 57.73±3.09
0.001 40.28±3.16 81.88±4.14 64.16±3.74 37.95±1.99 46.45±3.39 37.55±1.40
S-Hexylglutathione 0.1 71.98±1.76 94.93±0.65 97.08±0.92 67.84±1.10 76.91±0.26 64.14±3.58
0.01 24.87±3.93 63.18±3.21 75.44±0.61 32.07±1.58 20.09±1.24 35.03±2.46
Permethrin 0.01 35.56±1.68 20.37±1.90 27.36±5.45 35.87±1.87 47.73±3.08 11.70±1.87
Deltamethrin 0.01 40.15±2.17 11.01±7.51 30.72±3.53 35.28±3.05 49.30±2.37 15.87±5.29
λCyhalothrin 0.01 39.96±1.19 21.88±10.66 29.11±2.88 26.38±1.73 40.50±1.40 23.26±5.58