Table 1.
Characteristics of PARS SAA participants by olfactory status.a
| Characteristic | Hyposmic (N = 71) | Normosmic (N = 25) | Estimate (95% CI)b |
|---|---|---|---|
| Demographics | |||
| Median age at CSF collection (IQR) — yr | 65 (62–74) | 63 (55–66) | 1.93 (−2.35 to 6.22) |
| Male sex — no. (%) | 46 (65) | 12 (48) | 1.35 (0.87–2.10) |
| Race or ethnic group — no. (%)c | 1.13 (0.96–1.33) | ||
| White, non-Hispanic | 65 (92) | 20 (80) | |
| Hispanic or Latinx | 0 (0) | 3 (12) | |
| Black, non-Hispanic | 1 (1) | 0 (0) | |
| Missing data | 5 (7) | 2 (8) | |
| 1st-degree relative(s) with PD — no. (%) | 35 (49) | 19 (76) | 0.65 (0.47–0.90) |
| Key baseline biomarker | |||
| α-syn SAA result — no. (%)d | 11.97 (1.73–82.95) | ||
| Positive | 34 (48) | 1 (4) | |
| Negative | 37 (52) | 24 (96) |
a
IQR denotes interquartile range.
b
Estimates (median differences for continuous measures, relative risks for categorical measures) and 95% confidence intervals have not been adjusted for multiplicity and should not be used in place of hypothesis testing.
c
Race or ethnic group was reported by the participants. The associated relative risk compares non-Hispanic White to all other non-missing groups.
d
Adjustment for 1st-degree relative(s) with PD yielded a similar relative risk (95% CI): 12.15 (1.77–83.32). For simplicity, the unadjusted values are reported.