Table 6.
Multi-drug resistance profile of potential neonatal pathogen isolates identified from pregnant women and their newborns in public health facilities in Dessie town, Northeast Ethiopia, 2023.
| Isolated bacteria | Source | Degree of resistance | Total MDR | |||||
|---|---|---|---|---|---|---|---|---|
| R0 | R1 | R2 | R3 | R4 | ≥R5 | |||
| GBS | Maternal (12) | 1 (8.3) | 7 (58.3) | 2 (16.7) | 1 (8.3) | 1 (8.3) | 0 (0) | 2 (16.7) |
| Newborn (5) | 1 (20.0) | 1 (20.0) | 1 (20.0) | 1 (20.0) | 1 (20.0) | 0 (0) | 2 (40) | |
| S. aureus | Maternal (17) | 6 (35.3) | 5 (29.4) | 3 (17.6) | 3 (17.6) | 0 (0) | 0 (0) | 3 (17.6) |
| Newborn (7) | 2 (28.6) | 1 (14.3) | 2 (28.6) | 2 (28.6) | 0 (0) | 0 (0) | 2 (28.6) | |
| E. coli | Maternal (97) | 2 (2.1) | 41 (42.3) | 17 (17.5) | 14 (14.4) | 7 (7.2) | 17 (17.5) | 38 (39.2) |
| Newborn (56) | 0 (0) | 23 (41.1) | 11 (19.6) | 12 (21.4) | 6 (10.7) | 4 (7.1) | 22 (39.3) | |
| Klebsiella spp. | Maternal (21) | 0 (0) | 4 (19.0) | 7 (33.3) | 5 (23.8) | 2 (9.5) | 3 (14.3) | 10 (47.6) |
| Newborn (12) | 0 (0) | 2 (16.7) | 4 (33.3) | 3 (25) | 2 (16.7) | 1 (8.3) | 6 (50.0) | |
| Acinetobacter spp. | Maternal (11) | 2 (18.2) | 5 (45.5) | 0 (0) | 2 (18.2) | 0 (0) | 2 (18.2) | 4 (36.4) |
| Newborn (6) | 1 (16.7) | 3 (50.0) | 0 (0) | 1 (16.7) | 0 (0) | 1 (16.7) | 2 (33.3) | |
| Total | Maternal (158) | 10 (6.3) | 62 (39.2) | 29 (18.4) | 25 (15.8) | 10 (6.3) | 22 (13.9) | 57 (36.1) |
| Newborn (86) | 4 (4.7) | 30 (34.9) | 18 (20.9) | 19 (22.1) | 9 (10.5) | 6 (6.9) | 34 (39.5) | |
| Overall (244) | 14 (5.7) | 92 (37.7) | 47 (19.3) | 44 (18) | 19 (7.8) | 28 (11.5) | 91 (37.3) | |
n, Number of tested strains; R0, no resistance; R1, resistant to one class of antibiotics; R2, resistant to two class of antibiotics; R3, resistant to three class of antibiotics; R4, resistant to four class of antibiotics; ≥R5, resistant to five and above class of antibiotics; MDR, Multi Drug Resistance.