Table 3.

RoB assessment of the included studies

Study	Representativeness of the exposed cohort	Selection of the non-exposed cohort	Ascertainment of exposure	Demonstration that outcome of interest was not present at start of the study	Comparability of cohorts	Assessment of outcome	Was follow up long enough for outcomes to occur	Adequacy	Total
Eun S et al. (2019)	+	–	+	+	++	+	+	+	8
Gaig P et al. (2004)	+	–	–	+	++	–	+	+	6
Jo YH et al. (2022)	+	–	+	+	++	+	+	+	8
Wertenteil S et al. (2019)	+	–	+	+	++	+	+	+	8
Asero R et al. (2020)	+	+	+	+	++	+	+	+	9
Gregoriou et al. (2009)	+	–	+	+	++	+	+	+	8
Savic S et al. (2020)	+	–	+	+	+	+	+	–	7
Aktar S. et al. (2015)	+	+	+	+	++	+	+	+	9
Kolkhir P et al. (2020)	+	–	+	+	+	+	+	+	7
Kurt E et al. (2011)	+	–	+	+	+	+	+	+	7
Anis O et al. (2023)	+	+	+	+	++	+	+	+	9
Chen H et al. (2016)	+	–	+	+	+	+	+	+	7
Chiu HY et al. (2018)	+	–	+	+	++	+	+	+	8
Confino-Cohen R et al. (2012)	+	+	+	+	++	+	+	+	9
Ghazanfar M et al. (2020)	+	+	+	+	++	+	+	+	9
Gupta P et al. (2023)	+	–	+	+	++	+	+	+	8
Kolkhir P et al. (2021)	+	–	+	+	++	+	+	+	8
Kokaturk E et al. (2021)	+	–	+	+	+	+	+	+	7
Grieco T et al. (2020)	+	–	+	+	++	+	+	+	8
Tagka A et al. (2021)	+	–	+	+	++	+	+	+	8
Sirufo M et al. (2021)	+	–	+	+	++	+	+	+	8
Sommer R. et al. (2020)	+	–	+	+	++	+	+	+	8
De Ue et al. (2011)	+	–	+	+	++	+	+	+	8
Erol K et al. (2020)	+	–	+	+	++	+	+	+	8
Sanchez-Diaz M et al. (2023)	+	–	+	+	++	+	+	+	8
Silvares M et al. (2011)	+	–	+	+	++	+	+	+	8