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[Preprint]. 2025 Jan 28:2025.01.28.635252. [Version 1] doi: 10.1101/2025.01.28.635252

Extended Data Fig. 4: Validation of transcriptional changes in co-cultured neurons and astrocytes.

Extended Data Fig. 4:

Gene expression trends of selected genes at various time points after co-culture of human NPCs and mouse glia, along with the corresponding ANOVA test p-value. The human neurons showed significant upregulation of synaptic genes SVB2 and SYT1. Thebon mouse glia showed significant upregulation of synaptic adhesion genes Nrxn1 and Nlgn1 as well as Srebf2, a gene implicated in cholesterol biosynthesis.