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Measure of disproportionality and signal generation criteria.
| Methods | Formula | Signal standard |
|---|---|---|
| ROR |
|
A ≥ 3
|
| MHRA |
|
A ≥ 3 PRR ≥ 2
|
| BCPNN |
IC-2SD = E(IC)-2 |
A ≥ 3 IC-2SD > 0 |
,
are the Dirichlet distribution parameters, 
, 
,
, 
are Beta distribution parameters, IC-2SD is the lower limit of IC 95%CI, hypothesis 
, 
, E is the expected number of cases.
SD standard deviation.
