Table 4.

Pathway significance. This table shows the number of samples (out of 117) in the van 't Veer data set with pathway status active (+) or inactive (-) and with Group Sample Score p-value ≤ 0.05. Also shown are the corresponding family-wise p-values. ER notation as in Table 1.

Pathway	+	-	family-wise p-value
ER-induced	30	37	2e-55
EDAR	30	30	6e-46
IL-1	25	34	1e-44
RANK	29	30	1e-44
TNF-α	29	29	2e-43
EGF network	29	29	2e-43
ER	28	29	4e-42
ER-induced(v)	21	34	1e-39
TLR4	28	27	1e-39
fMLP	24	31	1e-39
Insulin	22	21	6e-26
ER (v)	17	21	6e-21
TGFβ network	20	18	6e-21
c-Kit	20	14	3e-17
ER-repressed (v)	11	17	4e-12
VEGF	11	15	1e-10
IL-10	12	13	7e-10
IFN	11	14	7e-10
PRL	11	14	7e-10
TPO	10	14	3e-09
PDGF	9	12	4e-07
Oncostatin M	6	15	4e-07
T-cell antigen receptor	11	8	6e-06
B-cell antigen receptor	11	7	2e-05
IL-12 – STAT4	7	9	2e-04
ER-repressed	7	6	6e-03
IL-2 – STAT5	5	7	1e-02
IL-4 – STAT6	5	3	2e-01
Wnt	4	4	2e-01