Table 1.

Baseline pulmonary artery pressure (PAP) and phorbol-12-myristate-13-acetate (PMA)-induced changes in PAP after 3 hours of normoxic ventilation. Pulmonary artery pressure values (PAP) are given for time points directly before and 6 min after addition of PMA to the buffer fluid. In addition, the increase in PAP per minute (ΔPAP/min) after PMA addition is indicated. Data are shown for experiments in the absence (-SOD) and the presence of 150 U/ml superoxide dismutase (+SOD). The PMA was added after 3 h of normoxic ventilation. Values of the +SOD and -SOD group correspond to experiments in Fig. 4. In the apocynin group this agent was present in the perfusate at a concentration of 500 μM. In experiments without addition of PMA, no significant change in PAP was observed within 6 min after PMA addition. Asterisk indicates significant difference of the -SOD as compared to the +SOD or apocynin group.

	directly before PMA [mmHg]	6 min after PMA	ΔPAP/min after PMA	n
-SOD	10.4 ± 0.4	15.2 ± 1.1	0.66 ± 0.18	5
+SOD	8.9 ± 0.7	9.9 ± 0.7	0.15 ± 0.02	4 *
apocynin	8.2 ± 0.4	8.3 ± 1.0	0.03 ± 0.01	4 *