Table III-1c. Group 2B carcinogens.
| Substance | CAS No. | Year of proposal |
|---|---|---|
| Acetamide | 60-35-5 | ʼ91 |
| Acetoaldehyde | 75-07-0 | ʼ91, (ʼ21) |
| Acrolein | 107-02-8 | ’23 |
| Acrylic acid methyl | 96-33-3 | ʼ19 |
| o-Aminoazotoluene | 97-56-3 | ʼ91 |
| p-Aminoazobenzene | 60-09-3 | ʼ91 |
| 2-Amino-4-chlorophenol | 95-85-2 | ʼ19 |
| Amitrole | 61-82-5 | ʼ86 |
| Aniline† | 62-53-3 | ’24 |
| Anthracene | 120-12-7 | ’23 |
| o-Anisidine (o-anisidine hydrochloride) | 90-04-0 | ʼ91, (ʼ96), (ʼ22) |
| Anthraquinone | 84-65-1 | ʼ15 |
| Auramine (technical grade) | 492-80-8 | ʼ86 |
| Benzofuran | 271-89-6 | ʼ15 |
| Benzophenone | 119-61-9 | ʼ15 |
| Benzoyl chloride | 98-88-4 | ʼ16 |
| Benzyl violet 4B | 1694-09-3 | ʼ91 |
| 2,2-Bis (bromomethyl) propane-1,3-diol | 3296-90-0 | ʼ01 |
| Bitumens | 8052-42-4 | ʼ91 |
| 1-Bromo-3-chloropropane | 109-70-6 | ’20 |
| Bromodichloromethane | 75-27-4 | ʼ95 |
| 1-Bromopropane | 106-94-5 | ʼ17 |
| 1-tert-Butoxy-2-propanol | 57018-52-7 | ʼ18 |
| n-Butyl-2,3-epoxypropyl ether | 2426-08-6 | ʼ16 |
| β-Butyrolactone | 3068-88-0 | ʼ95 |
| Carbon black | 1333-86-4 | ʼ91 |
| Carbon tetrachloride | 56-23-5 | ʼ86 |
| Catechol | 120-80-9 | ʼ01 |
| Chlordane | 57-74-9 | ʼ01 |
| Chlordecone (Kepone) | 143-50-0 | ʼ01 |
| Chlorendic acid | 115-28-6 | ʼ91 |
| Chlorinated paraffins | — | ʼ91 |
| p-Chloroaniline | 106-47-8 | ʼ95 |
| 4-Chlorobenzotrifluoride | 98-56-6 | ’20 |
| Chloroform | 67-66-3 | ʼ86, (ʼ05) |
| 1-Chloro-2-methylpropene | 513-37-1 | ʼ01 |
| 3-Chloro-2-methylpropene | 563-47-3 | ʼ01, (ʼ17) |
| Chlorophenoxy acetic acid herbicides* | — | ʼ86 |
| p-Chloro-o-phenylenediamine | 95-83-0 | ʼ91 |
| Chloroprene | 126-99-8 | ʼ01 |
| Chlorothalonil | 1897-45-6 | ʼ01 |
| CI acid red 114 | 6459-94-5 | ʼ95 |
| CI basic red 9 | 569-61-9 | ʼ95 |
| CI direct blue 15 | 2429-74-5 | ʼ95 |
| CI direct blue 218 | 28407-37-6 | ’21 |
| Citrus red No.2 | 6358-53-8 | ʼ91 |
| Cobalt and compounds (Without tungsten carbide)* | 7440-48-4 | ʼ95, (ʼ16) |
| p-Cresidine | 120-71-8 | ʼ91 |
| Crotonaldehyde | 4170-30-3 | ’21 |
| Cumene | 98-82-8 | ʼ15, (ʼ19) |
| Dantron | 117-10-2 | ʼ15 |
| N,N’-Diacetyl benzidine | 613-35-4 | ʼ91 |
| 2,4-Diaminoanisole | 615-05-4 | ʼ91 |
| 4,4’-Diaminodiphenyl ether | 101-80-4 | ʼ91 |
| 2,4-Diaminotoluene | 95-80-7 | ʼ91 |
| Diazinon | 333-41-5 | ʼ18 |
| 1,2-Dibromo-3-chloropropane | 96-12-8 | ʼ91 |
| 2,3-Dibromopropan-1-ol | 96-13-9 | ʼ01 |
| p-Dichlorobenzene | 106-46-7 | ʼ91, (ʼ98) |
| 3,3’-Dichlorobenzidine | 91-94-1 | ʼ86 |
| 1,4-Dichloro-2-butene | 764-41-0 | ʼ15 |
| 3,3’-Dichloro-4,4’-diaminodiphenyl ether | 28434-86-8 | ʼ91 |
| 1,2-Dichloroethane | 107-06-2 | ʼ91 |
| 1,4-Dichloro-2-nitrobenzene | 89-61-2 | ʼ19 |
| 2,4-Dichloro-1-nitrobenzene | 611-06-3 | ʼ19 |
| 1,3-Dichloropropene (technical grade) | 542-75-6 | ʼ91 |
| 1,3-Dichloro-2-propanol | 96-23-1 | ʼ15 |
| Dichlorvos | 62-73-7 | ʼ01 |
| Diepoxybutane | 1464-53-5 | ʼ91 |
| Diethanolamine | 111-42-2 | ʼ15 |
| Di (2-ethylhexyl) phthalate | 117-81-7 | ʼ91 |
| 1,2-Diethylhydrazine | 1615-80-1 | ʼ91 |
| Diglycidyl resorcinol ether | 101-90-6 | ʼ91 |
| Diisopropyl sulfate | 2973-10-6 | ʼ95 |
| N,N-Dimethylacetamide | 127-19-5 | ʼ19, (ʼ24) |
| p-Dimethylaminoazobenzene | 60-11-7 | ʼ91 |
| 2,6-Dimethylaniline | 87-62-7 | ʼ95 |
| 3,3’-Dimethylbenzidine (o-Tolidine) | 119-93-7 | ʼ91 |
| 1,1-Dimethylhydrazine | 57-14-7 | ʼ91 |
| Dimethyl hydrogen phosphite | 868-85-9 | ’23 |
| N,N-Dimethyl-p-toluidine | 99-97-8 | ʼ17 |
| 3,3’-Dimethoxybenzidine (o-Dianisidine) | 119-90-4 | ʼ86 |
| 2,4-(or 2,6-) Dinitrotoluene | 121-14-2 | ʼ98 |
| 1,4-Dioxane | 123-91-1 | ʼ86, (ʼ15) |
| Diphenylamine | 122-39-4 | ’22 |
| Disperseblue 1 | 2475-45-8 | ʼ91 |
| DDT | 50-29-3 | ʼ86, (ʼ17) |
| 1,2-Epoxybutane | 106-88-7 | ʼ01 |
| Ethyl acrylate | 140-88-5 | ʼ91, (ʼ19) |
| Ethylbenzene | 100-41-4 | ʼ01, (ʼ20) |
| 2-Ethylhexyl acrylate | 103-11-7 | ʼ19 |
| Ethyl methanesulphonate | 62-50-0 | ʼ91 |
| Ethylene thiourea | 96-45-7 | ʼ86 |
| Ethylenimine | 151-56-4 | ʼ01, (ʼ18) |
| (2-Formylhydrazino)-4-(5-nitro-2-furyl) thiazole | 3570-75-0 | ʼ91 |
| Furan | 110-00-9 | ʼ01 |
| Furfuryl alcohol | 98-00-0 | ʼ19 |
| Gasoline | 8006-61-9 | ʼ01 |
| Glycidaldehyde | 765-34-4 | ʼ91 |
| Glyphosate | 1071-83-6 | ’21 |
| HC blue No. 1 | 2784-94-3 | ʼ95 |
| Heptachlor | 76-44-8 | ʼ01 |
| Hexachlorocyclohexanes | 319-84-6 | ʼ91 |
| Hexachloroethane | 67-72-1 | ʼ22 |
| Hexamethylphosphoramide | 680-31-9 | ʼ01 |
| Isophorone | 78-59-1 | ’22 |
| Isoprene | 78-79-5 | ʼ95, (ʼ17) |
| Lead and compounds (Except alkyl lead)* | 7439-92-1 | ʼ91, (ʼ16) |
| Magenta (Containing CI basic red 9) | 632-99-5 | ʼ95 |
| Magnetic fields, extremely low-frequency | — | ʼ15 |
| Malathion | 121-75-5 | ʼ18 |
| Man-made mineral fibers (Ceramic fibers, Micro glass fibers) |
— | ʼ91, ʼ03 |
| Melamine | 108-78-1 | ʼ19 |
| 2-Mercaptobenzothiazole | 149-30-4 | ʼ19 |
| 4,4’-Methylene bis (2-methylaniline) | 838-88-0 | ʼ91 |
| 4,4’-Methylenedianiline | 101-77-9 | ʼ91, (ʼ95) |
| Methyl isobutyl ketone | 108-10-1 | ʼ15, (ʼ24) |
| Methyl mercuries | 7439-97-6 | ʼ95 |
| 2-Methyl-1-nitroanthraquinone | 129-15-7 | ʼ91 |
| N-Methyl-N-nitrosourethane | 615-53-2 | ʼ91 |
| N-Methylolacrylamide | 924-42-5 | ’22 |
| α-Methylstyrene | 98-83-9 | ʼ15 |
| Mirex | 2385-85-5 | ʼ01 |
| Molybdenum trioxide | 1313-27-5 | ʼ17 |
| β-Myrcene | 123-35-3 | ʼ18 |
| Naphthalene | 91-20-3 | ʼ15 |
| Nickel compounds (Except nickel carbonyl and nickel smelting dusts)* | 7440-02-0 | ʼ81, ʼ86, ʼ91, (ʼ09) |
| 2-Nitroanisole | 91-23-6 | ʼ98, (ʼ22) |
| 4-Nitroanisole | 100-17-4 | ʼ19 |
| Nitrobenzene | 98-95-3 | ʼ98 |
| o-Nitrochlorobenzene | 88-73-3 | ʼ19 |
| p-Nitrochlorobenzene | 100-00-5 | ʼ19 |
| Nitrilotriacetic acid and its salts | 139-13-9 | ʼ91 |
| Nitrogen mustard-N-oxide | 126-85-2 | ʼ91 |
| 5-Nitroacenaphtene | 602-87-9 | ʼ91 |
| Nitromethane | 75-52-5 | ʼ01 |
| 2-Nitropropane | 79-46-9 | ʼ91 |
| N-Nitrosodiethanolamine | 1116-54-7 | ʼ01 |
| N-Nitroso-N-phenylhydroxylamine ammonium salt (Cupferron) | 135-20-6 | ’21 |
| N-Nitrosomorpholine | 59-89-2 | ʼ91 |
| Oil orange SS | 2646-17-5 | ʼ91 |
| PAHs (Benz[a]anthracene, Benz[j]aceanthrylene, Benzo[b]fluoranthene, Benzo[c]phenanthrene, Benzo[j]fluoranthene, Benzo[k]fluoranthene, Chrysene, Dibenz[a, h]acridine, Dibenz[c, h]acridine, Dibenzo[a, h]pyrene, Dibenzo[a, i]pyrene, 7H-Dibenzo[c, g]carbazole, 1,3-Dinitropyrene, 1, 6- Dinitropyrene, 1,8-Dinitropyrene, 5-Methylchrysene, 3-Nitrobenzanthrone, 4-Nitropyrene) | 56-55-3, 202-33-5, 205-99-2, 195-19-7, 205-82-3, 207-08-9, 218-01-9, 226-36-8, 224-53-3, 189-64-0, 189-55-9, 194-59-2, 75321-20-9, 42397-64-8, 42397-65-9, 3697-24-3, 17117-34-9, 57835-92-4 |
ʼ16 |
| Perfluorooctanoic acid | 335-67-1 | ʼ17 |
| Phenyl glycidyl ether | 122-60-1 | ʼ91 |
| o-Phenylenediamine and its dihydrochloride | 95-54-5, 615-28-1 |
ʼ19 |
| Polybrominated biphenyls | 59536-65-1 | ʼ91, (ʼ17) |
| Polychlorophenols (technical grades) | — | ʼ86 |
| Ponceau 3R | 3564-9-8 | ʼ91 |
| Ponceau MX | 3761-53-3 | ʼ91 |
| β-Propiolactone | 57-57-8 | ʼ91 |
| Propylene imine (2-Methylaziridine) | 75-55-8 | ʼ91, (ʼ17) |
| Propylene oxide | 75-56-9 | ʼ91, ʼ95 |
| Pyridine | 110-86-1 | ʼ18 |
| Quinoline | 91-22-5 | ʼ18 |
| Radiofrequency electromagnetic fields | — | ʼ15 |
| 1,1,2,2-Tetrachloroethane | 79-34-5 | ʼ15 |
| Tetrachloroethylene | 127-18-4 | ʼ91, (ʼ01) |
| Tetrafluoroethylene | 116-14-3 | ʼ01, (ʼ17) |
| 2,4,6-Trichlorophenol | 88-06-2 | ʼ18 |
| Tetrabromobisphenol A | 79-94-7 | ʼ19 |
| Tetrahydrofuran | 109-99-9 | ʼ19 |
| Tetranitromethane | 509-14-8 | ʼ98 |
| 4,4’-Thiodianiline | 139-65-1 | ʼ91 |
| Thiourea | 62-56-6 | ʼ95 |
| Titanium dioxide | 13463-67-7 | ʼ15 |
| Toluene diisocyanates (TDI) | 26471-62-5 | ʼ91 |
| Trimethylolpropane Triacrylate (technical grade) | 15625-89-5 | ʼ19 |
| Trypane blue | 72-57-1 | ʼ91 |
| Urethane | 51-79-6 | ʼ91 |
| Vanadium pentoxide | 1314-62-1 | ʼ15 |
| Vinylidene chloride | 75-35-4 | ʼ18 |
| Vinyl acetate | 108-05-4 | ʼ98 |
| 4-Vinylcyclohexene | 100-40-3 | ʼ95 |
| 4-Vinylcyclohexene diepoxide | 106-87-6 | ʼ95 |
*Evaluation does not necessarily apply to all individual chemicals within the group.
†Provisional
( ) in the year of proposal indicates year of reconsideration resulting in no classification change.
Antimony trioxide and 2-bromopropane are proposed to be excluded from Group 2B†.