Table 1.
Outcomes of endotherapy in patients with pancreas divisum and recurrent acute pancreatitis.
| Study, year | Study type | n | Classification | Endotherapy | Technical success (%) | Clinical success (%) | Follow-up | Adverse events |
|---|---|---|---|---|---|---|---|---|
| Lans, 199213 | RCT | 19 | RAP 10, Control 9 |
Dilatation + stenting | NR | 90% | 28.6 m | 0% |
| Lehman, 199314 | P | 52 | CAP 24 RAP 17 CP 11 |
MiES + stent | NR | 26.1% 76.5% 27.3% |
1.7 y | 15% |
| Gerke, 200421 | R | 53 | RAP 30 CP 14 CAP 9 |
MiES + stent | NR | RAP 43.3% CP 21.4% CAP 11.1% |
29 m | 11.2% |
| Chacko, 200820 | R | 57 | RAP 27 CP 20 CAP 8 |
Majority MiES (94%) | 86% | RAP 76% CP 42% CAP 33% |
20 m | 11.7% |
| Borak, 200919 | R | 113 | RAP 62 CP 22 CAP 29 |
MiES + stent | NR | RAP 53.2% CP 18.2% CAP 41.4% |
43 m | 13.3% |
| Rustagi, 201322 | R | 45 | RAP 18 CP 7 CAP 13 |
MiES ± stent (majority) | 91.9% | RAP 94% CP 57% CAP 50% |
NR | 16.1% |
| Tringali, 201918 | R | 48 | RAP | MiES ± stent | NR | 72.9% | 9.7 y | 12.9% |
| De Jong, 202126 | Multicentre, R | 81 | RAP 66 CP 12 CAP 3 |
MiES + stent | 74.1% | RAP 44.4% CP 33.3% CAP 33.3% |
≥3 m | 37% |
Abbreviations: CP, chronic pancreatitis; CAP, chronic abdominal pain; MiES, minor papilla sphincterorotomy; NR, nonresponse; RAP, recurrent acute pancreatitis; P, prospective; R, retrospective; RCT, randomized controlled trial.