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. 2025 Feb 21;24:64. doi: 10.1186/s12944-025-02492-y

Table 4.

Weighted subgroup analysis of association between METS-IR and hypertension

Variable OR (95% CI), P-value P-interaction
Age (years) < 0.001
≤ 40 1.05 (1.04–1.06), < 0.001
> 40 to ≤ 60 1.02 (1.01–1.04), < 0.001
> 60 1.02 (1.01–1.04), < 0.001
Sex 0.646
Male 1.04 (1.03–1.05), < 0.001
Female 1.03 (1.03–1.04), < 0.001
Race 0.430
Mexican-American 1.04 (1.02–1.06), < 0.001
Other Hispanic 1.04 (1.02–1.05), < 0.001
Non-Hispanic White 1.04 (1.03–1.04), < 0.001
Non-Hispanic Black 1.03 (1.02–1.04), < 0.001
Other, including multiple 1.05 (1.03–1.07), < 0.001
Education level < 0.001
< 9th grade 1.04 (1.02–1.06), < 0.001
9–11th grade (Includes 12th grade without diploma) 1.03 (1.01–1.05), 0.004
High school graduate/GED 1.01 (1.00–1.03), 0.058
Some college or 2-year degree 1.04 (1.03–1.05), < 0.001
College degree or beyond 1.05 (1.04–1.06), < 0.001
Marital status 0.037
Married 1.04 (1.03–1.05), < 0.001
Widowed 1.00 (0.98–1.03), 0.702
Divorced 1.03 (1.01–1.05), < 0.001
Separated 1.02 (0.99–1.04), 0.219
Never married 1.03 (1.02–1.04), < 0.001
Living with partner 1.03 (1.01–1.05), 0.006
Poverty-to-income ratio 0.009
≤ 1 1.02 (1.01–1.03), 0.005
> 1 to ≤ 3 1.03 (1.02–1.04), < 0.001
> 3 1.04 (1.03–1.05), < 0.001
Diabetes 0.030
Yes 1.02 (1.00–1.04), 0.024
No 1.05 (1.04–1.05), < 0.001
Coronary heart disease 0.612
Yes 1.04 (1.02–1.06), < 0.001
No 1.03 (1.03–1.04), < 0.001
Stroke 0.508
Yes 1.02 (0.99–1.06), 0.119
No 1.04 (1.03–1.04), < 0.001
Smoking 0.337
Yes 1.02 (1.00–1.05), < 0.001
No 1.04 (1.03–1.04), < 0.001
Alcohol consumption, drinks/day 0.09
≤ 5 1.05 (1.04–1.05), < 0.001
> 5 1.03 (1.01–1.05), 0.012

CI, confidence interval; METS-IR, Metabolic Score for Insulin Resistance; OR, odds ratio