Table 2.2:

Consistency Between Extracted Histology and IHC/FISH Results

		Chromophobe RCC	Papillary RCC	CCPRCT	Clear cell RCC	TFE3 Rearranged RCC	TFEB Altered RCC
Total Number of Specimens †		84	119	62	1630	6	5
CAIX	Expected → Extracted ↓	Negative	Focal/Patchy Positive or Negative	Positive (Cup-Like)	Positive or Positive (Box-Like)	Negative	Negative
	Positive (Cup-Like)	0	1^	61	3^	0	0
	Positive (Box-Like)	0	0	2*	164	0	0
	Focal/Patchy Positive	0	22	0	6*	0	1
	Other Positive‡	0	6	3	548	0	0
	Negative	24	15	0	2*	5	3
CD117	Expected → Extracted ↓	Positive	Negative	Negative	Negative	Negative	Negative
	Positive	87	0	0	1^	0	1*
	Negative	0	4	6	26	2	3
Racemase	Expected → Extracted ↓	Negative	Positive	Negative	Mixed	Mixed	Mixed
	Focal/Patchy Positive	0	2	0	7	0	0
	Positive/Diffuse Positive	2*	99	0	9	1	2
	Negative	3	0	13	4	0	0
TFE3	Expected → Extracted ↓	Negative	Negative	Negative	Negative	Rearranged	Negative
	Rearranged	0	0	0	0	6	0
	Negative	2	7	0	6	0	4
TFEB	Expected → Extracted ↓	Negative	Negative	Negative	Negative	Negative	Rearranged/Amplified
	Rearranged/Amplified	0	0	0	0	0	5
	Negative	2	6	0	4	6	0

^†Single specimens may have multiple tests, thus column totals may be higher than the number of specimens

^‡Includes “Positive” alone, or with other modifiers not explicitly Focal/Patchy, Cup-Like, or Box-Like

^*Report reviewed and the LLM corrected a typographic mistake (STable 5 for details)

^{^}Report reviewed and the LLM found to have made a mistake (STable 5 for details)