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. 2005 Jun 21;389(Pt 1):181–186. doi: 10.1042/BJ20041677

Figure 1. Molecular cloning of PLC-η.

Figure 1

(A) The predicted amino acid sequence of human PLC-η. (B) Schematic representation of the predicted domain features of human PLC-η. PH, X, Y and C2 represent their respective domains. (C) Alignment of amino acid sequences corresponding to the X and Y domains of PLCs. The amino acid sequence of PLC-η is compared with PLC-β1, PLC-γ1 and PLC-δ1. Identical amino acids are boxed. The amino acids indicated with arrows are known to be essential for PLC activity. (D) Dendrogram illustrating phylogeny of CLUSTAL W aligned mammalian PLC sequences.