Figure 3. Organization of the PLC-η gene.
A linear presentation of the exon locus shows the relative positions and approximate sizes of 24 exons spanning 200 kb (human) or 160 kb (mouse) of chromosome 3. (A) The cDNA co-ordinates for the exons of human gene are as follows: 1, 1–43; 2, 44–190; 3, 191–435; 4, 436–564; 5, 565–735; 6, 736–829; 7, 830–1033; 8, 1034–1154; 9, 1155–1327; 10, 1328–1434; 11, 1435–1596; 12, 1597–1668; 13, 1669–1760; 14, 1761–1858; 15, 1859–2038; 16, 2039–2146; 17, 2147–2271; 18, 2272–2356; 19, 2357–2503; 20, 2504–2583; 21, 2584–2643; 22, 2644–2998; 23, 2999–3026; 24, 3027–6196; 25, 2999–3208. (B) Schematic presentation of splicing variants (see the Results and discussion section). (a) hPLC-ηa (GenBank® accession no. AY691170), (b) hPLC-ηb (GenBank® accession no. AY691171) and (c) hPLC-ηc (GenBank® accession no. XM_042635). (C) The cDNA co-ordinates for the exons of mouse gene are as follows: 1, 1–43; 2, 44–190; 3, 191–435; 4, 436–565; 5, 566–735; 6, 736–829; 7, 830–1033; 8, 1034–1154; 9, 1155–1326; 10, 1327–1434; 11, 1435–1596; 12, 1597–1668; 13, 1669–1763; 14, 1764–1861; 15, 1862–2040; 16, 2041–2149; 17, 2150–2274; 18, 2275–2359; 19, 2360–2506; 20, 2507–2586; 21, 2587–2646; 22, 2647–3001; 23, 3002–3024 or 3029; 24, 3025 or 3030–6273. (D) Schematic presentation of splicing variants (see the Results and discussion section). (a) mPLC-ηa (GenBank® accession no. AY691172), (b) mPLC-ηb (GenBank® accession no. AY691173) and (c) mPLC-ηc (GenBank® accession no. AY691174).