. 2025 Jan 24;44(1):93-103. doi: 10.5937/jomb0-51740

Table 1. Distribution of thalassemia genotypes in 1174 cases.

Groups	Types	Genotypes	Number of cases (n)	Proportion (%)
Static α-thalassemia	Deletion	-α^3.7/αα	72	11.67
		-α^4.2/αα	40	6.48
	Non-deletion type 1	α^CSα/αα	57	9.24
		α^QSα/αα	7	1.13
	Non-deletion type 2	α^WSα/αα	13	2.11
Mild α-thalassemia	Deletion	—^SEA/aa	365	59.16
		-α^3.7/-α^3.7	8	1.30
		-α^4.2/-α^4.2	1	0.16
		-α^3.7/-α^4.2	1	0.16
	Non-deletion	-α^3.7/α^CSα	3	0.49
		α^CSα/α^QSα	3	0.49
		α^CSα/α^CSα	2	0.32
Intermediate α-thalassemia	Deletion	—^SEA/-α^3.7	23	3.73
		—^SEA/-α^4.2	5	0.81
	Non-deletion	—^SEA/αCSα	16	2.59
		—^SEA/α^WSα	1	0.16
Mild β-thalassemia	β⁺/β^N	β^IVS-II-⁶⁵⁴/β^N	72	14.06
		β^E/β^N	16	3.13
		β^-28/β^N	5	0.98
		β^-29/β^N	3	0.59
		β^Cap/β^N	2	0.39
	β⁰/β^N	β^CD17/β^N	211	41.21
		β^CD41-42/β^N	166	32.42
		β^CD71-72/β^N	7	1.37
		β^CD43/β^N	6	1.17
		β^CD27-28/β^N	2	0.39
		β^CD14-15/β^N	1	0.20
Intermediate β-thalassemia	β⁺/β⁺	β^-28/β^-28	2	0.39
Severe β-thalassemia	β⁺/β⁰	β^CD17/β^E	5	0.98
		β^CD41-42/β^-28	2	0.39
		β^-29/β^CD17	1	0.20
		β^-29/β^CD27-28	1	0.20
		β^CD41-42/β^E	2	0.39
	β⁰/β⁰	β^CD17/β^CD17	3	0.59
		β^CD41-42/β^CD17	3	0.59
		β^CD41-42/β^CD41-42	1	0.20
		β^CD41-42/β^CD27-28	1	0.20
Coinheritance of static α-thalassemia<br>and mild β-thalassemia	-α^3.7/αα; β^CD17/β^N	12	26.67
	-α^4.2/αα; β^CD41-42/β^N	6	13.33
	α^CS/αα; β^CD17/β^N	4	8.89
	-α^3.7/αα; β^CD41-42/β^N	3	6.67
	-α^3.7/αα; β^IVS-II-654/β^N	2	4.44
	-α^4.2/αα; β^CD17/β^N	3	6.67
	α^QS/αα; β^CD41-42/β^N	1	2.22
	-α^3.7/αα; β^E/β^N	1	2.22
Coinheritance of mild α-thalassemia<br>and mild β-thalassemia	—^SEA/αα; β^CD17/β^N	3	6.67
	—^SEA/αα; β^CD41-42/β^N	4	8.89
	—^SEA/αα; β^IVS-II-654/β^N	1	2.22
	-α^3.7/-α^3.7; β^CD17/β^N	1	2.22
Coinheritance of intermediate<br>α-thalassemia and mild β-thalassemia	—^SEA/α^CSα; β^CD17/β^N	2	4.44
	—^SEAα^CSα; β^CD41-42/β^N	1	2.22
Coinheritance of intermediate<br>α-thalassemia and severe β-thalassemia	—^SEA/α^CSα; β^CD17/β^CD17	1	2.22
Total			1174	100