Table 4. The multivariate analysis results.
| Risk factors | No. of study | Heterogeneity | ES (Effect size, 95% CI) | P | P of Egger | |
|---|---|---|---|---|---|---|
| I2 (%) | P | |||||
| Age | 4 | 12.8 | 0.329 | 0.01 (−0.02, 0.04) | 0.477 | 0.188 |
| BMI | 2 | 0 | 0.462 | −0.35 (−0.65, −0.05) | 0.021 | <0.001 |
| Male | 2 | 80 | 0.025 | −0.35 (−1.53, 0.83) | 0.565 | <0.001 |
| eGFR, mL/min | 3 | 80.1 | 0.007 | 0.00 (−0.02, 0.02) | 0.999 | 0.153 |
| Pulmonary hypertension before surgery | 2 | 76.1 | 0.410 | 0.24 (−1.05, 1.54) | 0.711 | <0.001 |
| Diabetes | 2 | 0 | 0.708 | 0.05 (−0.71, 0.80) | 0.870 | <0.001 |
| Pulmonary hypertension | 2 | 46.1 | 0.173 | 0.38 (−1.15, 1.91) | 0.623 | <0.001 |
| Cystic fibrosis | 2 | 0 | 0.975 | 0.77 (0.24, 1.30) | 0.040 | <0.001 |
| Double lung transplantation | 4 | 0 | 0.446 | 1.09 (0.59, 1.58) | <0.001 | 0.722 |
| Cardiopulmonary bypass | 2 | 0 | 0.564 | 0.00 (0.00, 0.01) | 0.018 | <0.001 |
| Intra-op ECMO | 4 | 0 | 0.876 | 0.09 (−0.43, 0.61) | 0.742 | 0.526 |
| Duration of mechanical ventilation | 3 | 96.5 | <0.001 | 0.17 (−2.79, 3.13) | 0.909 | 0.638 |
| Post-op ECMO | 2 | 14.9 | 0.278 | 1.55 (0.15, 2.96) | 0.030 | <0.001 |
| Mechanical ventilation >3 d | 2 | 82.3 | 0.018 | 0.77 (−1.08, 2.62) | 0.416 | <0.001 |