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. 2025 Feb 21;13:e18364. doi: 10.7717/peerj.18364

Table 4. The multivariate analysis results.

Risk factors No. of study Heterogeneity ES (Effect size, 95% CI) P P of Egger
I2 (%) P
Age 4 12.8 0.329 0.01 (−0.02, 0.04) 0.477 0.188
BMI 2 0 0.462 −0.35 (−0.65, −0.05) 0.021 <0.001
Male 2 80 0.025 −0.35 (−1.53, 0.83) 0.565 <0.001
eGFR, mL/min 3 80.1 0.007 0.00 (−0.02, 0.02) 0.999 0.153
Pulmonary hypertension before surgery 2 76.1 0.410 0.24 (−1.05, 1.54) 0.711 <0.001
Diabetes 2 0 0.708 0.05 (−0.71, 0.80) 0.870 <0.001
Pulmonary hypertension 2 46.1 0.173 0.38 (−1.15, 1.91) 0.623 <0.001
Cystic fibrosis 2 0 0.975 0.77 (0.24, 1.30) 0.040 <0.001
Double lung transplantation 4 0 0.446 1.09 (0.59, 1.58) <0.001 0.722
Cardiopulmonary bypass 2 0 0.564 0.00 (0.00, 0.01) 0.018 <0.001
Intra-op ECMO 4 0 0.876 0.09 (−0.43, 0.61) 0.742 0.526
Duration of mechanical ventilation 3 96.5 <0.001 0.17 (−2.79, 3.13) 0.909 0.638
Post-op ECMO 2 14.9 0.278 1.55 (0.15, 2.96) 0.030 <0.001
Mechanical ventilation >3 d 2 82.3 0.018 0.77 (−1.08, 2.62) 0.416 <0.001