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. 2025 Jan 28;22:100881. doi: 10.1016/j.resplu.2025.100881

Table 5.

Multivariate analysis for clinical outcomes.

CPC 3-5
In-hospital mortality
2-year mortality
OR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value
Age, years 1.001 (0.985–1.038) 0.396 0.997 (0.986–1.009) 0.651 1.002 (0.990–1.013) 0.775
Male§ 0.950 (0.381–2.370) 0.912 0.855 (0.594–1.231) 0.400 0.928 (0.653–1.317) 0.675
Arrest at public§ 0.623 (0.278–1.398) 0.251 0.836 (0.570–1.226) 0.360 0.919 (0.631–1.337) 0.658
Shockable rhythm§ 0.202 (0.069–0.590) 0.003 0.574 (0.330–0.999) 0.050 0.431 (0.253–0.732) 0.002
Bystander CPR§ 0.446 (0.199–1.001) 0.050 0.659 (0.451–0.963) 0.031 0.660 (0.458–0.952) 0.026
Asphyxia§ 1.021 (0.229–4.549) 0.978 0.822 (0.533–1.268) 0.376 1.046 (0.682–1.606) 0.836
Cardiac cause§ 0.316 (0.087–1.147) 0.080 0.660 (0.403–1.082) 0.100 0.877 (0.558 –1.379) 0.570
Heart failure§ 1.793 (0.340–9.438) 0.491 1.172 (0.699–1.963) 0.547 1.074 (0.654–1.763) 0.777
AKI§ 7.684 (2.683–22.010) <0.001 1.868 (1.079–3.231) 0.026 2.159 (1.272–3.664) 0.004

CPC 3-5 In-hospital mortality 2-year mortality

OR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value

Age, years 1.010 (0.978–1.044) 0.543 0.999 (0.987–1.011) 0.861 1.003 (0.991–1.015) 0.636
Male§ 1.229 (0.396–3.816) 0.721 0.709 (0.482–1.042) 0.080 0.708 (0.487–1.030) 0.071
Arrest at public§ 0.958 (0.363–2.528) 0.931 1.080 (0.720–1.620) 0.709 1.035 (0.702–1.526) 0.861
Shockable rhythm§ 0.280 (0.080–0.973) 0.045 0.916 (0.523–1.607) 0.760 0.723 (0.408–1.279) 0.265
Bystander CPR§ 0.465 (0.180–1.203) 0.114 0.612 (0.405–0.926) 0.020 0.655 (0.441–0.974) 0.037
Asphyxia§ 0.745 (0.103–5.402) 0.771 0.918 (0.577–1.463) 0.720 1.046 (0.662–1.653) 0.848
Cardiac cause§ 0.292 (0.062–1.367) 0.118 0.664 (0.400–1.102) 0.113 0.781 (0.483–1.263) 0.314
Heart failure§ 5.015 (0.535–47.030) 0.158 1.198 (0.703–2.040) 0.506 1.172 (0.700–1.961) 0.546
AKI without recovery§ 5.275 (2.049–13.583) <0.001 7.637 (4.210–13.855) <0.001 5.470 (3.034–9.862) <0.001

CPC 3-5 In-hospital mortality 2-year mortality

OR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value

Age, years 1.107 (0.991–1.044) 0.195 1.000 (0.989–1.012) 0.934 1.004 (0.993–1.015) 0.482
Male§ 0.923 (0.380–2.237) 0.858 0.800 (0.555–1.154) 0.232 0.835 (0.586–1.191) 0.320
Arrest at public§ 0.614 (0.278–1.355) 0.227 0.894 (0.607–1.315) 0.569 0.944 (0.647–1.378) 0.765
Shockable rhythm§ 0.310 (0.111–0.867) 0.026 0.844 (0.483–1.476) 0.553 0.641 (0.369–1.113) 0.114
Bystander CPR§ 0.422 (0.192–0.926) 0.031 0.579 (0.391–0.857) 0.006 0.610 (0.418–0.892) 0.011
Asphyxia§ 0.790 (0.184–3.388) 0.751 0.978 (0.636–1.506) 0.921 1.211 (0.792–1.851) 0.377
Cardiac cause§ 0.339 (0.098–1.177) 0.089 0.675 (0.414–1.099) 0.114 0.862 (0.545–1.361) 0.523
Heart failure§ 2.038 (0.363–11.459) 0.419 0.809 (0.481–1.361) 0.425 0.820 (0.497–1.353) 0.438
Impaired eGFRpredischarge§ 3.164 (1.442–6.940) 0.004 3.957 (2.554–6.131) <0.001 2.876 (1.861–4.443) <0.001

AKI, acute kidney injury; CI, confidence interval; CPC, cerebral performance category; CPR, cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; OR, odd ratio;

§

yes vs. no.