. 2025 Feb 11;14(2):180. doi: 10.3390/antibiotics14020180

Table 6.

Antimicrobial activity of CNPs and BEO:WSEO-CNPs.

Microorganism		Antimicrobial Activity (mg/mL)
Microorganism		Chitosan NPs	BEO:WSEO-NPs
Bacillus subtilis ATCC 663	MIC	3.26 ± 0.07 ^b	1.58 ± 0.04 ^a
Bacillus subtilis ATCC 663	MBC	6.43 ± 0.06 ^b	3.36 ± 0.12 ^a
Staphylococcus aureus ATCC 25923	MIC	3.12 ± 0.03 ^b	1.56 ± 0.17 ^a
Staphylococcus aureus ATCC 25923	MBC	6.25 ± 0.09 ^b	3.25 ± 1.10 ^a
Proteus vulgaris ATCC 8427	MIC	6.30 ± 0.24 ^b	3.12 ± 0.08 ^a
Proteus vulgaris ATCC 8427	MBC	6.37 ± 0.12 ^a	6.31 ± 0.08 ^a
Pseudomonas aeruginosa ATCC 27853	MIC	12.22 ± 0.08 ^b	6.25 ± 0.07 ^a
Pseudomonas aeruginosa ATCC 27853	MBC	15.43 ± 0.02 ^b	6.25 ± 0.04 ^a
Escherichia coli ATCC 25922	MIC	1.56 ± 0.05 ^a	1.49 ± 0.13 ^a
Escherichia coli ATCC 25922	MBC	6.28 ± 0.08 ^b	3.20 ± 0.21 ^a
Klebsiella pneumoniae ATCC 700603	MIC	6.68 ± 0.23 ^b	3.31 ± 0.12 ^a
Klebsiella pneumoniae ATCC 700603	MBC	12.50 ± 0.19 ^b	6.18 ± 0.41 ^a

CNPs—chitosan nanoparticles, BEO:WSEO-CNPs—chitosan-based nanoparticles loaded with basil and winter savory essential oils mixture in 2:1 ratio. Different letters indicate significant difference among the samples in the same row.