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. 2025 Feb 11;90(7):2636–2643. doi: 10.1021/acs.joc.4c02645

Table 5. Intramolecular and Intermolecular Competition Studies on the Effect of Base in Amidation reactionsa.

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entry base 4b (%) 2a (%) 6b (%) unknown (%)
1 triethylamine 23 8 3 2
2 2,6-lutidine 44 5 0 0
a

Yield was determined with 19F{1H}-NMR using α,α,α-trifluorotoluene as an internal standard.