AD	Alzheimer’s disease
ADME	absorption, distribution, metabolism, and excretion
ALS	amyotrophic lateral sclerosis
ATP	adenosine triphosphate
HbA1c	hemoglobin A1c
HD	Huntington’s disease
PD	Parkinson’s disease
PDC	pyruvate dehydrogenase complex
PPAR-γ	peroxisome proliferator-activated receptor gamma
IFD	induced fit docking
OMM	outer mitochondrial membrane
IMS	inner mitochondrial space
IMM	inner mitochondrial matrix
α-KG	α-ketoglutarate
FAO	fatty acid oxidation
OAA	oxaloacetate
ETC	electron transport chain
GGAA	glucogenic amino acid
KGAA	ketogenic amino acid
MCT	monocarboxylate transporter
MPC	mitochondrial pyruvate carrier
mTOR	mechanistic target of rapamycin
NAFLD	non-alcoholic fatty liver disease
NASH	non-alcoholic steatohepatitis
QSAR	quantitative structure–activity relationship
SAR	structure–activity relationship
TZD	thiazolidinedione
VDAC	voltage-dependent anion channel