Table 2.
Changes in gut microbiota in neurological disorders
| Condition | Bacteria | Result | |
|---|---|---|---|
| Increase | Decrease | ||
| Alzheimer disease | Pseudomonas | [159–161] | – |
| Escherichia | [163–166] | – | |
| Shigella | [163, 165, 166] | – | |
| B. thetaiotaomicron | [136] | – | |
| Bifidobacterium | – | [168–170] | |
| Lactobacillus | – | [170] | |
| Coprococcus | – | [163] | |
| Akkermansia | [200] | [176, 200] | |
| Parkinson’s Disease | Proteobacteria | [180, 182, 183] | – |
| Enterobacteriaceae | [181–183] | – | |
| Klebsiella | [187, 199] | – | |
| Coprococcus | – | [180] | |
| Blautia | – | [180, 190] | |
| Roseburia | – | [180] | |
| Bifidobacterium | [189, 190, 195] | – | |
| Gammaproteobacteria | [198, 199] | – | |
| Akkermansia | [200] | – | |
| Multiple sclerosis | Faecalibacterium prausnitzii | – | [205, 211] |
| Bifidobacterium | – | [206] | |
| Coprococcus | – | [206] | |
| Lachnospiraceae | – | [206] | |
| Butyricicoccus | – | [206] | |
| Akkermansia | [122, 200, 205, 211] | – | |
| Pseudomonas | [211] | – | |
| Blautia | [206, 210, 211] | [122, 205] | |
| Depression | Bifidobacterium | – | [121, 222, 232] |
| Lactobacillus | – | [222] | |
|
Faecalibacterium prausnitzii |
– | [121, 231, 232] | |
| Blautia | [121] | – | |
| Escherichia | [232] | [121] | |
| Shigella | [232] | [121] | |
| Klebsiella | [121] | – | |
| Coprococcus | – | [96] | |
| Autism spectrum disorder | Klebsiella | [123, 242] | – |
| Clostiridium species | [123] | [246] | |
| Bifidobacterium | – | [123, 243] | |
| Escherichia | [245–247] | – | |
The associations between neurological disorders (Alzheimer's disease, Parkinson’s disease, multiple sclerosis, depression, and autism) and bacteria (genus or species). The sources of these associations range from the latest studies (in humans or rodents) to review papers. The PubMed query used was: ((Genus) OR (Species)) AND ((Alzheimer's disease) OR (Parkinson's disease) OR (Multiple sclerosis) OR (Depression) OR (Autism))