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. 2025 Feb 18;17(4):694. doi: 10.3390/cancers17040694
ICI immune checkpoint inhibitor
CAR-T chimeric antigen receptor-T
TNF-α tumor necrosis factor α
NF-κB nuclear factor κB
PD-1 programmed cell death 1
PD-L1 programmed cell death 1-ligand 1
CTLA-4 cytotoxic T-lymphocyte-associated antigen 4
OS overall survival
PFS progression-free survival
ORR objective response rate
SBRT stereotactic body radiation therapy
FDA U.S. Food and Drug Administration
EMA European Medicines Agency
TMB tumor mutation burden
VEGF vascular endothelial growth factor
VEGFR vascular endothelial growth factor receptor
FGFR fibroblast growth factor receptor
PDGFR platelet-derived growth factor receptor
DC dendritic cell
shRNA short hairpin ribonucleic acid
miRNA micro ribonucleic acid
MSC mesenchymal stromal cells
TTFields tumor-treating fields