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. 2025 Feb 25;10:15. doi: 10.1186/s40834-025-00346-7

Table 2.

Pooled estimate of the odds ratio of infertility by menarche age

menarche age Number of evidence Sample size (expose group) Sample size (non-expose) Pooled estimate of the odds ratio of infertility Publication Bias total
(Egger test)
Sensitivity analysis result (Yes, No) * Heterogeneity
OR (95% CI) Significant impact of menarche age on the infertility (Yes, No) β P-value I−square; % p−value for Q
Early vs. late menarche age 21 11,340 6164 0.77(0.55, 1.06) No 0.60 0.590 No 85.6 < 0.001
Early vs. normal menarche age 11 5950 52,905 0.98 (0.68, 1.42) No 0.63 0.637 No 85.7 < 0.001
late vs. normal menarche age 11 1782 52,905 1.44(0.98, 2.10) No -0.27 0.842 No 79.6 < 0.001

*Is there a significant difference in the impact of each of the primary studies on the overall estimate?