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. 2005 Jul 14;6:12. doi: 10.1186/1471-2091-6-12

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Copyright © 2005 Bellemare et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Alignment of the amino acid sequence of mouse 17α-HSD with those of related enzymes. Amino acid sequence of mouse 17α-HSD was aligned with sequences of mouse (m), rat (r), rabbit (rb) and human (h) enzyme members of the AKR1c subfamily. The corresponding name according to the nomenclature for aldo-keto reductase (AKR) family members are: m17α-HSD, AKR1C21; m3α-HSD, AKR1C14; m20α-HSD, AKR1C18; m17β-HSD5, AKR1C6; r3α-HSD, AKR1C9; r20α-HSD, AKR1C8; h3α-HSD1, AKR1C4; h3α-HSD3, AKR1C2; h17β-HSD5 or 3α-HSD2, AKR1C3; and h20α-HSD, AKR1C1. Amino acids are given in conventional single letter code and numbered on the right. Dashes and dots, respectively, represent identical and missing amino acids.