Table 2.
Sr. No. | p16 protein expression | p16 gene alteration | ||
Deletion | Mutation | p16 promoter methylation | ||
1. | - | - | - | + / - |
2. | - | - | - | + / - |
3. | - | + | - | - / - |
4. | - | - | + | - / + |
5. | + | - | - | + / + |
6. | - | - | - | + / - |
7. | - | + | - | - / - |
8. | - | - | - | + / - |
9. | - | - | - | + / - |
10. | + | - | + | - / + |
11. | - | - | - | + / - |
12. | - | + | - | - / - |
13. | - | - | - | + / - |
14. | + | - | - | + / + |
15. | - | - | - | + / - |
16. | - | - | - | - / + |
17. | - | - | + | - / + |
18. | - | - | - | + / - |
19. | + | - | - | - / + |
20. | + | - | - | - / + |
21. | - | - | + / - | |
22. | + | - | + | - / + |
23. | - | - | - | + / - |
24. | + | - | - | - / + |
25. | - | - | - | - / + |
+ / + : Completely methylated
- / - : Unmethylated
+ / - : Partially methylated