Skip to main content
. 2025 Feb 14;26(4):1651. doi: 10.3390/ijms26041651
MASH/NASH non-alcoholic steatohepatitis
MAFLD/NAFLD non-alcoholic fatty liver disease
T2DM type 2 diabetes mellitus
PKA protein kinase A
PI3K phosphatidylinositol-3-kinase
AKT/PKB protein Kinase B
AMPK adenosine 5‘-monophosphate (AMP)-activated protein kinase
MAPK mitogen-activated protein kinase
PPARγ peroxisome proliferator-activated receptor γ
FABP4 fatty acid-binding protein 4
BMP4 bone morphogenetic protein 4
UCP1 uncoupling protein 1
ARC activity-regulated cytoskeleton-associated protein
AgRP agouti-related protein
NPY neuropeptide Y
GIP gastric inhibitory polypeptide
GIPR gastric inhibitory polypeptide receptor
GCG glucagon
GCGR glucagon receptor
NTS nucleus tractus solitarius
AOM azoxymethane
FDA food and drug administration
TAG triacylglycerol
WAT white adipose tissue
HbA1c glycosylated hemoglobin, type A1C
CCK cholecystokinin
PYY peptide YY
mTOR mammalian target of rapamycin
mTORC1 mechanistic target of rapamycin complex 1
mTORC2 mechanistic target of rapamycin complex 2
GLUT4 glucose transporter 4
GSK3 glycogen synthase kinase-3
MAPKKK mitogen-activated protein kinase kinase kinase
BAT brown adipose tissue
p38-MAPK p38 mitogen-activated protein kinase
ERK extracellular signal-related kinases
ERK5 extracellular signal-related kinases 5
ERK1/2 extracellular signal-related kinases 1/2
TCF transcription factor
C1EBPα/CCAAT enhancer-binding proteins
ADD1 adducin 1
APM acute poliomyelitis
GSK3β glycogen synthase kinase 3 β
OSBPL2 oxysterol binding protein-like 2
CXXC5 CXXC finger protein 5
NOTUM notum palmitoleoyl-protein carboxylesterase