Table 5.
Univariate and multivariate logistic regression analysis of non-treated hypopituitarism determinants (continuous variables) performed in patients with central hypothyroidism (n = 90) (A). Additionally, regression analyses were performed with the use of all hospitalization time points, i.e., n = 90 + 34 = 124; additional 34 hospitalization time points were recorded at the 2nd and the 3rd time point for 30 patients) (B). Only statistically significant determinants, or when justified, are presented in the univariate analysis. Statistical significance was determined at the level of p < 0.05. Statistically significant differences are shaded.
| (A) | ||||||
| Variable | Patients with Central Hypothyroidism (n = 90) | |||||
| Univariate Regression | Multivariate Regression | |||||
| OR | 95%Cl | p | OR | 95%Cl | p | |
| IGF-1 | 0.991 | 0.983–0.999 | 0.024 | - | - | - |
| (B) | ||||||
| Variable | All Samples (n = 124) | |||||
| Univariate Regression | Multivariate Regression | |||||
| OR | 95%Cl | p | OR | 95%Cl | p | |
| ACTH [pg/mL] | 0.960 | 0.928–0.994 | 0.021 | 0.964 | 0.928–1.001 | 0.055 |
| IGF-1 | 0.987 | 0.979–0.994 | <0.001 | 0.985 | 0.975–0.996 | 0.005 |