Table 3.
Multivariate cox regression model in the training cohort.
| Variables | OS | P value | CSS | P value |
|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | |||
| Age at diagnose (years) | ||||
| < 77 | Reference | Reference | ||
| ≥ 77 | 2.591 (1.993, 3.367) | 0.000 | 1.515 (1.081, 2.123) | 0.016 |
| Distant metastasis | ||||
| No | Reference | Reference | ||
| Yes | 3.134 (1.614, 6.084) | 0.001 | 4.060 (1.989, 8.287) | 0.000 |
| AJCC stage | ||||
| I–II | Reference | Reference | ||
| III–IV | 1.543 (1.070, 2.226) | 0.020 | 1.833 (1.075, 3.125) | 0.026 |
| Type of surgery | ||||
| Total or radical parotidectomy | Reference | Reference | ||
| Local parotidectomy | 0.715 (0.542, 0.944) | 0.018 | 0.624 (0.432, 0.901) | 0.012 |
| Regional nodes positive | ||||
| < 4 | Reference | Reference | ||
| ≥ 4 | 1.152 (0.827, 1.605) | 0.404 | 1.518 (1.026, 2.246) | 0.037 |
| Tumor size (mm) | ||||
| < 28 | Reference | Reference | ||
| ≥ 28 | 1.726 (1.309, 2.277) | 0.000 | 1.523 (1.062, 2.183) | 0.022 |