Table 1.
Summary statistics for the mean of each phenotype across C57B6 and 42 Collaborative Cross (CC) mouse strains. The table outlines the minima (lowest value), first quantile (25th percentile), median, mean, third quantile (75th percentile), and maxima (highest value) of the calculated means across all mouse strains. SA is vector specific activity. It is measured as the ratio of luciferase expression at week 24-PVA and expressed as photon/s/vector-genome/cell.
Luc W1 photon/s |
Luc W3 photon/s |
Luc W6 photon/s |
Luc W8 photon/s |
Luc W14 photon/s |
Luc W24 photon/s |
|||
---|---|---|---|---|---|---|---|---|
Min | 960,125 | 670,875 | 614,943 | 640,300 | 978,000 | 1,016,900 | −0.625 | −0.158 |
First Quantile | 4,735,500 | 4,040,833 | 5,517,083 | 4,660,000 | 5,528,750 | 5,524,792 | 0.036 | 0.140 |
Median | 7,154,583 | 12,271,667 | 14,277,083 | 12,921,700 | 14,581,267 | 14,131,083 | 0.421 | 0.308 |
Mean | 16,051,377 | 22,468,382 | 25,291,655 | 26,118,529 | 26,426,337 | 25,063,259 | 0.519 | 0.386 |
Third Quantile | 19,337,500 | 22,962,083 | 30,437,188 | 30,902,917 | 35,147,708 | 32,247,500 | 0.984 | 0.617 |
Max | 96,837,500 | 177,962,500 | 163,275,000 | 178,150,000 | 193,912,500 | 130,412,500 | 2.150 | 1.619 |
Liver VCN
Vector-genome/Cell |
Spleen VCN
Vector-genome/Cell |
Vector SA
(Specific Activity) |
||||||
Min | −0.419 | −0.522 | −0.481 | −0.158 | 0.045 | 0.039 | 0.434 | 6,897,779 |
First Quantile | −0.058 | −0.099 | 0.148 | 0.140 | 0.256 | 0.108 | 1.809 | 21,511,854 |
Median | 0.020 | 0.093 | 0.467 | 0.308 | 0.387 | 0.159 | 3.053 | 41,832,255 |
Mean | 0.088 | 0.156 | 0.461 | 0.386 | 0.471 | 0.194 | 3.665 | 60,354,896 |
Third Quantile | 0.234 | 0.267 | 0.726 | 0.617 | 0.602 | 0.218 | 4.329 | 84,925,752 |
Max | 0.627 | 1.220 | 1.561 | 1.619 | 1.911 | 0.783 | 12.175 | 228,820,708 |