Table 3.

Association between eGDR levels with all-cause mortality, cardiovascular specific mortality, and diabetes specific mortality of CMS participants in different glucose metabolic states at baseline

	All-cause mortality (Model 3)		Cardiovascular specific mortality (Model 3)		Diabetes specific mortality (Model 3)
	HR (95%CI)	P	HR (95%CI)	P	HR (95%CI)	P
Baseline DM
Continuous	0.92 (0.87–0.97)	0.004	0.89 (0.81–0.98)	0.016	0.89 (0.81–0.97)	0.012
Q1	Ref		Ref		Ref
Q2	0.63 (0.47–0.84)	0.002	0.58 (0.35–0.96)	0.033	0.46 (0.29–0.73)	0.001
Q3	0.73 (0.55–0.95)	0.025	0.80 (0.50–1.30)	0.373	0.39 (0.23–0.67)	< 0.001
Q4	0.73 (0.53–1.00)	0.048	0.63 (0.37–1.08)	0.095	0.47 (0.28–0.79)	0.005
p-trend		0.124		0.237		0.008
Baseline Pre-DM
Continuous	0.95 (0.90–1.01)	0.099	0.89 (0.80–0.98)	0.021	0.71 (0.55–0.91)	0.008
Q1	Ref		Ref		Ref
Q2	0.85 (0.66–1.08)	0.172	0.58 (0.38–0.88)	0.011	0.21 (0.07–0.65)	0.007
Q3	0.75 (0.56–1.01)	0.059	0.55 (0.34–0.88)	0.014	0.19 (0.07–0.54)	0.002
Q4	0.79 (0.56–1.10)	0.159	0.52 (0.28–0.96)	0.037	0.10 (0.03–0.34)	< 0.001
p-trend		0.119		0.040		< 0.001
Baseline NGR
Continuous	0.88 (0.76–1.02)	0.083	0.80 (0.63–1.03)	0.080	0.21 (0.08–0.60)	0.003

eGDR: Estimated glucose disposal rate; CMS: Cardiometabolic syndrome; HR: Hazard ratios; CI: Confidence interval; DM: Diabetes mellitus; Pre-DM: Pre-diabetes mellitus; NGR: Normal glucose regulation